Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9233712 | 0.89 | KDM4E (0.37) | KDM4EALDH1A1GLAPOLBKMT2A | |
| SCHEMBL9230821 | 0.76 | GRIA1 (0.61) | KDM4EALDH1A1GLAKMT2AGRIA1 | |
| SCHEMBL9231432 | 0.68 | THRB (0.39) | ALDH1A1KMT2ALMNAHPGDNPSR1 | |
| SCHEMBL10684512 | 0.66 | MMP8 (0.61) | ALDH1A1POLBLMNANPSR1MAPT | |
| SCHEMBL8634867 | 0.66 | GRIN2D (0.44) | GRIA1GRIA2GRIA3GRIA4HSD17B10 | |
| SCHEMBL1831636 | 0.66 | MMP8 (0.61) | ALDH1A1POLBLMNANPSR1MAPT | |
| SCHEMBL7948487 | 0.66 | HSD17B10 (0.44) | KDM4EALDH1A1GRIA1GRIA2GRIA3 | |
| SCHEMBL604459 | 0.66 | MMP8 (0.61) | ALDH1A1POLBLMNANPSR1MAPT | |
| SCHEMBL7586256 | 0.65 | CYP1A2 (0.36) | KDM4EALDH1A1KMT2AHSD17B10LMNA | |
| SCHEMBL9386398 | 0.65 | BLM (0.63) | KDM4EALDH1A1POLBKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832074-B1 | AMINO ACID DERIVATIVES OF SUBSTITUTED QUINOXALINE 2,3-DIONE DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 2002-09-04 | — | — | EP | disclosed |
| WO-1996040649-A1 | AMINO ACID DERIVATIVES OF SUBSTITUTED QUINOXALINE 2,3-DIONE DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1996-12-19 | — | — | WO | disclosed |