SCHEMBL31022673

SCHEMBL31022673

NC(=S)Nc1ccccc1Br

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 1.00
ALDH1A1 P00352 4/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
KDM4E B2RXH2 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
TP53 P04637 1/20 0.50
TYR P14679 1/20 0.50
TSHR P16473 1/20 0.50
TAS2R38 P59533 1/20 0.50
HSD17B10 Q99714 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
NPC1 O15118 3/20 0.49
RAB9A P51151 2/20 0.48
HTT P42858 2/20 0.48
LMNA P02545 1/20 0.48
PKM P14618 1/20 0.47
CYP1A2 P05177 2/20 0.47
CYP3A4 P08684 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2357864 1.00 L3MBTL1 (1.00) L3MBTL1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL7593748 0.84 L3MBTL1 (0.71) L3MBTL1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL8436453 0.83 L3MBTL1 (0.71) L3MBTL1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL31388330 0.82 L3MBTL1 (0.69) L3MBTL1ALDH1A1MEN1KMT2AMAPT
SCHEMBL9454012 0.82 L3MBTL1 (0.69) L3MBTL1ALDH1A1MEN1KMT2AMAPT
SCHEMBL30521404 0.80 L3MBTL1 (0.67) L3MBTL1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL21712227 0.80 L3MBTL1 (0.67) L3MBTL1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL2050021 0.80 L3MBTL1 (0.67) L3MBTL1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL28600570 0.78 L3MBTL1 (0.64) L3MBTL1ALDH1A1MEN1KMT2ATAS2R38
SCHEMBL11877272 0.78 L3MBTL1 (0.64) L3MBTL1ALDH1A1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12528798-B2 Compound for crop protectant LG CHEM, LTD. (KR) 2026-01-20 US disclosed
US-20240246945-A1 NOVEL COMPOUND FOR CROP PROTECTANT LG CHEM, LTD. (KR) 2024-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240246945-A1 NOVEL COMPOUND FOR CROP PROTECTANT KEAP1, BROX, GPX1 L3MBTL1 1593/4885ALDH1A1 2249/4885MEN1 4024/4885
US-12528798-B2 Compound for crop protectant CBR1, CBR3, GSTO1 L3MBTL1 222/4885ALDH1A1 2445/4885MEN1 3228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.