Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.42 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7611163 | 0.83 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1MAPK1FAAHCYP3A4 | |
| SCHEMBL2097862 | 0.81 | HDAC3 (0.59) | SMN1; SMN2ALDH1A1MAPK1FAAHCYP3A4 | |
| SCHEMBL515008 | 0.80 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1MAPTLMNAGAA | |
| SCHEMBL716889 | 0.78 | MAPK1 (0.62) | SMN1; SMN2ALDH1A1MAPK1FAAHCYP3A4 | |
| SCHEMBL7028479 | 0.77 | RXFP1 (0.42) | SMN1; SMN2MAPTLMNAMEN1KMT2A | |
| SCHEMBL2092939 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1MAPK1FAAHCYP3A4 | |
| SCHEMBL7032860 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAGAAMEN1KMT2A | |
| SCHEMBL14368009 | 0.74 | MAPT (0.59) | SMN1; SMN2ALDH1A1MAPK1FAAHCYP3A4 | |
| SCHEMBL11653085 | 0.73 | MGLL (0.58) | SMN1; SMN2ALDH1A1MAPK1FAAHCYP3A4 | |
| SCHEMBL13154805 | 0.73 | MAPK1 (0.62) | SMN1; SMN2ALDH1A1MAPK1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257528-A1 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001060786-A1 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-23 | — | — | WO | disclosed |