Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1547824 | 0.80 | KMT2A (0.49) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL7741833 | 0.77 | CA12 (0.47) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL196635 | 0.76 | KMT2A (0.49) | CA12CA2CA9MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2238154 | 0.74 | KMT2A (0.47) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL11973878 | 0.74 | KMT2A (0.47) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL11973371 | 0.74 | KMT2A (0.47) | CA12CA2CA9MEN1KMT2A | |
| Ethane SCHEMBL7405342 | 0.74 | KMT2A (0.47) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL29367590 | 0.72 | OPRM1 (0.47) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL29170174 | 0.72 | CYP2C19 (0.44) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL1532229 | 0.72 | RXFP1 (0.48) | CA12CA2CA9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384282-B2 | CATALYST IS REACTION PRODUCT OF GROUP 8 METAL AND LIGAND | YALE UNIVERSITY | 2002-05-07 | — | — | US | disclosed |
| US-20020016509-A1 | Transition metal-catalyzed process for addition of amines to carbon-carbon double bonds | YALE UNIVERSITY | 2002-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016509-A1 | Transition metal-catalyzed process for addition of amines to carbon-carbon double bonds | COASY, CMA1, ATIC | CA12 263/4885CA2 115/4885CA9 382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.