Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.42 |
| ▸ | ENPEP | Q07075 | 6/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10791525 | 0.84 | SLC1A1 (0.34) | GLRA1SLC6A9OR51E2 | |
| SCHEMBL27584091 | 0.80 | GRM8 (0.47) | PTGS1SLC7A11ENPEPANPEP | |
| SCHEMBL7175770 | 0.79 | GABRP (0.39) | GLRA1SLC6A9OR51E2 | |
| SCHEMBL2322429 | 0.79 | SLC7A5 (0.46) | ANPEP | |
| SCHEMBL27719619 | 0.79 | ENPEP (0.50) | PTGS1SLC7A11ENPEPANPEP | |
| SCHEMBL441814 | 0.79 | ENPEP (0.50) | PTGS1SLC7A11ENPEPANPEP | |
| SCHEMBL9791352 | 0.78 | ALOX15 (0.47) | — | |
| SCHEMBL10789456 | 0.78 | GSR (0.50) | CPB2 | |
| SCHEMBL8347563 | 0.78 | PTGS1 (0.35) | PTGS1SLC7A11 | |
| SCHEMBL98566 | 0.76 | GLRA1 (0.47) | GLRA1SLC6A9OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438600-B2 | ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF | SHISEIDO CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| US-6156555-A | Method of preparing an enzyme participating in C-terminal amidation | SHISEIDO COMPANY LTD. (JP) | 2000-12-05 | — | — | US | disclosed |
| EP-0666318-B1 | Enzyme participating in c-terminal amidation, and method of preparing same and use thereof | SHISEIDO CO LTD (JP) | 2000-11-29 | — | — | EP | disclosed |
| US-5871995-A | Purified enzymes participating in C-terminal amidation | SHISEIDO COMPANY, LTD. (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0884389-A1 | Enzyme participating in C-terminal amidation, and method of preparing same and use thereof | SHISEIDO COMPANY LIMITED (JP) | 1998-12-16 | — | — | EP | disclosed |
| EP-0438600-B1 | ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF | SHISEIDO CO LTD (JP) | 1996-02-07 | — | — | EP | disclosed |
| EP-0666318-A1 | Enzyme participating in c-terminal amidation, and method of preparing same and use thereof | SHISEIDO COMPANY LIMITED (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5354675-A | Amidation of glycine | SHISEIDO COMPANY LTD. (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0447547-B1 | C-TERMINUS AMIDATION ENZYME COMPOSITION, PROCESS FOR ITS PREPARATION AND ITS USE | SHISEIDO CO LTD (JP) | 1994-07-27 | — | — | EP | disclosed |
| EP-0447547-A1 | C-TERMINUS AMIDATION ENZYME COMPOSITION, PROCESS FOR ITS PREPARATION AND ITS USE | SHISEIDO COMPANY LIMITED (JP) | 1991-09-25 | — | — | EP | disclosed |
| EP-0438600-A1 | ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF | SHISEIDO COMPANY LIMITED (JP) | 1991-07-31 | — | — | EP | disclosed |