Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.53 |
| ▸ | PGR | P06401 | 7/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.51 |
| ▸ | AR | P10275 | 3/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.51 |
| ▸ | USP2 | O75604 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595133 | 0.87 | NR3C1 (0.63) | NR3C1PGRCYP3A4ARF2 | |
| SCHEMBL10427816 | 0.86 | PGR (0.67) | NR3C1PGRCYP3A4ARF2 | |
| SCHEMBL10427815 | 0.86 | PGR (0.67) | NR3C1PGRCYP3A4ARF2 | |
| SCHEMBL7596820 | 0.86 | PGR (0.61) | NR3C1PGRCYP3A4ARF2 | |
| SCHEMBL10427859 | 0.83 | PGR (0.66) | NR3C1PGRCYP3A4ARF2 | |
| SCHEMBL10356202 | 0.83 | PGR (0.66) | NR3C1PGRCYP3A4ARF2 | |
| SCHEMBL10356203 | 0.83 | PGR (0.66) | NR3C1PGRCYP3A4ARF2 | |
| SCHEMBL10427790 | 0.82 | PGR (0.64) | NR3C1PGRCYP3A4ARF2 | |
| SCHEMBL10427789 | 0.82 | PGR (0.64) | NR3C1PGRCYP3A4ARF2 | |
| SCHEMBL10803758 | 0.81 | PGR (0.70) | NR3C1PGRCYP3A4ARF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640616-B1 | 17-Alkylcarbonate, 21-0-carbonic/carboxylic acid esters of corticosteroids, a method for their production and pharmaceutical compositions containing them | HOECHST AG (DE) | 2002-11-27 | — | — | EP | claimed |
| EP-0640616-B1 | 17-Alkylcarbonate, 21-0-carbonic/carboxylic acid esters of corticosteroids, a method for their production and pharmaceutical compositions containing them | HOECHST AG (DE) | 2002-11-27 | — | — | EP | disclosed |
| EP-0640616-A2 | 17-Alkylcarbonate, 21-0-carbonic/carboxylic acid esters of corticosteroids, a method for their production and pharmaceutical compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-01 | — | — | EP | disclosed |