SCHEMBL7594286

SCHEMBL7594286

C=CC(O)c1ccccc1C(O)C=C

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
TSHR P16473 3/20 0.39
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
PCSK9 Q8NBP7 1/20 0.33
ORAI1 Q96D31 1/20 0.33
ORAI2 Q96SN7 1/20 0.33
ORAI3 Q9BRQ5 1/20 0.33
TRPV6 Q9H1D0 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
AKT1 P31749 1/20 0.32
CYP2C19 P33261 1/20 0.30
ALOX15 P16050 1/20 0.30
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15388937 0.93 ALDH1A1 (0.35) ALDH1A1TSHRGABRA1GABRB2
SCHEMBL646259 0.89 CYP3A4 (0.38) ALDH1A1TSHRMEN1KMT2AALOX15
SCHEMBL9555419 0.85 ALDH1A1 (0.33) ALDH1A1TSHRHDAC8
SCHEMBL9815785 0.85 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL526123 0.85 ALDH1A1 (0.48) ALDH1A1TSHRMEN1KMT2A
SCHEMBL387118 0.85 GABRA1 (0.48) ALDH1A1TSHRGABRA1GABRB2MEN1
SCHEMBL5614870 0.85 ALDH1A1 (0.33) ALDH1A1TSHRAKT1CYP2C19ALOX15
SCHEMBL2068749 0.84 IDO1 (0.36) ALDH1A1TSHRCYP2C19ALOX15
SCHEMBL5614611 0.84 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL11672242 0.84 ALDH1A1 (0.52) ALDH1A1TSHRATMCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0945420-B1 Process for the preparation of bisphenols MITSUI CHEMICALS INC (JP) 2002-06-12 EP claimed
US-6316677-B1 REACTING PHENOLIC COMPOUND WITH DIALKYLBENZENE, BIS(HYDROXYALKYL)BENZENE, OR (HYDROXYALKYL)-ALKENYLBENZENE; NEUTRALIZATION USING ANION EXCHANGE RESIN; CONCENTRATION, ISOLATION MITSUI CHEMICALS, INC. (JP) 2001-11-13 US claimed
EP-0945420-A1 Process for the preparation of bisphenols Mitsui Chemicals, Inc. (JP) 1999-09-29 EP claimed
US-4968759-A Phenolic polymer and production thereof HITACHI CHEMICAL COMPANY, LTD. (JP) 1990-11-06 US claimed
JP-11335312-A None JP disclosed
JP-61145223-A None JP disclosed
JP-62045658-A None JP disclosed
JP-2150454-A None JP disclosed
JP-61145255-A None JP disclosed
JP-63303939-A None JP disclosed
JP-61145224-A None JP disclosed
WO-2015051402-A1 ALKYLATION OF PHENOLIC COMPOUNDS THE UNIVERSITY OF SYDNEY (AU) 2015-04-16 WO disclosed
EP-0312872-A2 Graft copolymers, process for their manufacture and use thereof BAYER AG (DE) 1989-04-26 EP disclosed
JP-S63303939-A PRODUCTION OF BISPHENOLS MITSUI PETROCHEM IND LTD 1988-12-12 JP disclosed
JP-S6245658-A STABILIZED SYNTHETIC RESIN COMPOSITION HITACHI CHEM CO LTD 1987-02-27 JP disclosed
JP-S61145255-A STABILIZED SYNTHETIC RESIN COMPOSITION HITACHI CHEM CO LTD 1986-07-02 JP disclosed
JP-S61145223-A PRODUCTION OF PHENOLIC POLYMER HITACHI CHEM CO LTD 1986-07-02 JP disclosed
JP-S61145224-A PRODUCTION OF PHENOLIC POLYMER HITACHI CHEM CO LTD 1986-07-02 JP disclosed
US-3946014-A Process for preparing certain 1,3,4-dioxazol-2-ones and products ATLANTIC RICHFIELD COMPANY (US) 1976-03-23 US disclosed
JP-S06245658-A 0001-01-01 JP disclosed