Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 11/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5384431 | 0.85 | NPC1 (0.38) | HRH4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL532721 | 0.85 | NPC1 (0.38) | HRH4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29462567 | 0.84 | NPC1 (0.36) | HRH4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL22048825 | 0.84 | RAB9A (0.38) | HRH4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL20764391 | 0.83 | NPC1 (0.35) | HRH4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL22062300 | 0.83 | PLK4 (0.38) | HRH4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5388939 | 0.82 | RAB9A (0.41) | HRH4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL22871731 | 0.81 | PLK4 (0.38) | HRH4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL20195671 | 0.78 | NPC1 (0.39) | HRH4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL532241 | 0.72 | MAPT (0.38) | HRH4MEN1KMT2APLK4DAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235938-A2 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | Epoch Biosciences, Inc. (US) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001042505-A2 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES, INC. (US) | 2001-06-14 | — | — | WO | disclosed |