Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595122 | 1.00 | CNR1 (0.44) | CNR1CNR2ALDH1A1NPSR1BMP1 | |
| SCHEMBL7595148 | 0.92 | CNR1 (0.36) | CNR1CNR2OPRM1OPRD1 | |
| SCHEMBL7597597 | 0.92 | CNR1 (0.36) | CNR1CNR2OPRM1OPRD1 | |
| SCHEMBL7596641 | 0.90 | CNR1 (0.47) | CNR1CNR2ALDH1A1NPSR1BMP1 | |
| SCHEMBL7595822 | 0.90 | CNR1 (0.47) | CNR1CNR2ALDH1A1NPSR1BMP1 | |
| SCHEMBL7600358 | 0.87 | FOLH1 (0.43) | CNR1CNR2OPRM1OPRD1ATM | |
| SCHEMBL7595801 | 0.87 | FOLH1 (0.43) | CNR1CNR2OPRM1OPRD1ATM | |
| Hydrochloric Acid SCHEMBL7596742 | 0.86 | ALDH1A1 (0.41) | CNR1CNR2ALDH1A1NPSR1EPHX1 | |
| Hydrochloric Acid SCHEMBL7595022 | 0.86 | ALDH1A1 (0.41) | CNR1CNR2ALDH1A1NPSR1EPHX1 | |
| SCHEMBL7595770 | 0.86 | CNR1 (0.43) | CNR1CNR2ALDH1A1NPSR1BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | claimed |
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | claimed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | claimed |
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |