Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597597 | 1.00 | CNR1 (0.36) | CNR1CNR2OPRM1OPRD1OPRK1 | |
| SCHEMBL7595122 | 0.92 | CNR1 (0.44) | CNR1CNR2OPRM1OPRD1 | |
| SCHEMBL7594445 | 0.92 | CNR1 (0.44) | CNR1CNR2OPRM1OPRD1 | |
| SCHEMBL7596630 | 0.90 | TRPM8 (0.44) | CNR1CNR2OPRM1OPRD1OPRK1 | |
| SCHEMBL7595802 | 0.87 | TRPM8 (0.41) | CNR1CNR2EPHX2TRPM8NPY1R | |
| SCHEMBL7595142 | 0.87 | TRPM8 (0.41) | CNR1CNR2EPHX2TRPM8NPY1R | |
| SCHEMBL7594806 | 0.84 | HTR2A (0.40) | OPRM1OPRD1OPRK1TRPM8 | |
| SCHEMBL7600933 | 0.84 | FOLH1 (0.46) | — | |
| SCHEMBL7598858 | 0.84 | FOLH1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL7599219 | 0.83 | HTR2A (0.39) | OPRM1OPRD1OPRK1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | claimed |
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | claimed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | claimed |
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |