Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | BMP1 | P13497 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595822 | 1.00 | CNR1 (0.47) | CNR1CNR2BMP1ALDH1A1NPSR1 | |
| SCHEMBL7597372 | 0.93 | F2 (0.40) | CNR1CNR2BMP1TRPM8ALOX5 | |
| SCHEMBL7595802 | 0.92 | TRPM8 (0.41) | CNR1CNR2TRPM8ALOX5 | |
| SCHEMBL7595142 | 0.92 | TRPM8 (0.41) | CNR1CNR2TRPM8ALOX5 | |
| SCHEMBL7598459 | 0.92 | TRPM8 (0.49) | CNR1CNR2CASRTRPM8ALOX5 | |
| SCHEMBL7594442 | 0.91 | CNR1 (0.44) | CNR1CNR2BMP1ALDH1A1NPSR1 | |
| SCHEMBL7600900 | 0.91 | CNR1 (0.46) | CNR1CNR2BMP1ALDH1A1NPSR1 | |
| SCHEMBL7598031 | 0.90 | CNR1 (0.47) | CNR1CNR2BMP1ALDH1A1NPSR1 | |
| Iodide SCHEMBL7600457 | 0.90 | CNR1 (0.43) | CNR1CNR2BMP1ALDH1A1NPSR1 | |
| SCHEMBL7594445 | 0.90 | CNR1 (0.44) | CNR1CNR2BMP1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | claimed |
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |