Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594233 | 0.87 | SMN1; SMN2 (0.41) | LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL8415132 | 0.80 | SMN1; SMN2 (0.36) | ALDH1A1NPC1RAB9A | |
| SCHEMBL8416636 | 0.79 | SMN1; SMN2 (0.32) | ALDH1A1 | |
| SCHEMBL7591976 | 0.77 | SMN1; SMN2 (0.32) | ALDH1A1NPC1RAB9A | |
| SCHEMBL7589131 | 0.74 | HDAC3 (0.34) | LMNA | |
| SCHEMBL8415016 | 0.69 | SMN1; SMN2 (0.36) | ALDH1A1NPC1RAB9A | |
| SCHEMBL8416621 | 0.69 | HDAC3 (0.31) | — | |
| SCHEMBL468689 | 0.67 | — | — | |
| SCHEMBL5571787 | 0.67 | CYP2C19 (0.38) | TSHRMAPK1ALDH1A1CYP2C19 | |
| SCHEMBL8342120 | 0.66 | LMNA (0.47) | LMNATSHRMAPK1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448442-B1 | X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2002-09-10 | — | — | US | disclosed |