Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22645203 | 0.97 | LMNA (0.47) | LMNASMN1; SMN2ALDH1A1HPGDNPC1 | |
| Hydrochloric Acid SCHEMBL11285322 | 0.95 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL7591398 | 0.87 | ALDH1A1 (0.43) | LMNASMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL22661232 | 0.85 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL7595426 | 0.83 | ALDH1A1 (0.40) | LMNASMN1; SMN2ALDH1A1HPGDNPC1 | |
| Hydrochloric Acid SCHEMBL9451386 | 0.83 | LMNA (0.40) | LMNASMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL11286324 | 0.83 | SMN1; SMN2 (0.42) | LMNASMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL708587 | 0.83 | ALDH1A1 (0.42) | LMNASMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL11879797 | 0.81 | LMNA (0.55) | LMNASMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL7532896 | 0.81 | PKM (0.44) | SMN1; SMN2ALDH1A1HPGDNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003509-A2 | PHARMACEUTICAL PRODUCTS CONTAINING TRIIODOAROMATS CONTAINING PERFLUOROALKYL GROUPS, AND THE USE THEREOF IN THE TREATMENT OF TUMOURS AND INTERVENTIONAL RADIOLOGY | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-01-28 | — | — | WO | disclosed |