SCHEMBL759546

SCHEMBL759546

CC(=O)c1ccc(CSCc2ccccc2C)cc1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.60
MAPT P10636 6/20 0.60
KDM4E B2RXH2 1/20 0.60
MAOB P27338 1/20 0.54
ALDH1A1 P00352 5/20 0.49
HPGD P15428 2/20 0.49
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
KMT2A Q03164 2/20 0.46
HTT P42858 2/20 0.45
GLA P06280 1/20 0.44
TDP1 Q9NUW8 2/20 0.44
TSHR P16473 1/20 0.44
MEN1 O00255 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27818376 0.94 LMNA (0.55) LMNAMAPTKDM4EMAOBALDH1A1
SCHEMBL28901835 0.88 MAOB (0.54) LMNAMAPTKDM4EMAOBALDH1A1
SCHEMBL4880410 0.83 LMNA (0.53) LMNAMAPTKDM4EALDH1A1HPGD
SCHEMBL20371196 0.83 KMT2A (0.64) LMNAMAPTMAOBALDH1A1HPGD
SCHEMBL28687523 0.82 LMNA (0.51) LMNAMAPTKDM4EMAOBALDH1A1
SCHEMBL14541452 0.82 LMNA (0.67) LMNAMAPTKDM4EMAOBALDH1A1
SCHEMBL758838 0.80 LMNA (0.51) LMNAMAPTKDM4EALDH1A1HPGD
SCHEMBL28682455 0.79 LMNA (0.56) LMNAMAPTKDM4EALDH1A1HPGD
SCHEMBL14541578 0.79 MAOB (0.58) LMNAMAPTKDM4EMAOBALDH1A1
SCHEMBL756535 0.77 MAPT (0.53) LMNAMAPTKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12529144-B2 Composition, method of producing substrate, and polymer JSR CORPORATION (JP) 2026-01-20 US disclosed
WO-2024237033-A1 COMPOSITION FOR SEMICONDUCTOR DEVICE PROCESSING AND METHOD FOR PRODUCING MODIFIED SUBSTRATE 富士フイルム株式会社 2024-11-21 WO disclosed
US-12065534-B2 Composition, method of producing substrate, and polymer JSR CORPORATION (JP) 2024-08-20 US disclosed
CN-115210322-B Resin composition, wiring board, and method for producing conductive pattern 东丽株式会社 2023-10-20 CN disclosed
US-11525067-B2 Modification method of substrate surface, and composition and polymer JSR CORPORATION (JP) 2022-12-13 US disclosed
CN-115210322-A Resin composition, wiring board, and method for producing conductive pattern 东丽株式会社 2022-10-18 CN disclosed
US-11422464-B2 Photosensitive resin composition, method of producing electrically conductive pattern, substrate, touch panel, and display TORAY INDUSTRIES, INC. (JP) 2022-08-23 US disclosed
US-20220259741-A1 COMPOSITION, METHOD OF PRODUCING SUBSTRATE, AND POLYMER JSR CORPORATION (JP) 2022-08-18 US disclosed
CN-109791352-B Photosensitive resin composition, method for producing conductive pattern, substrate, touch panel, and display 东丽株式会社 2022-07-29 CN disclosed
US-20220089809-A1 COMPOSITION, METHOD OF PRODUCING SUBSTRATE, AND POLYMER JSR CORPORATION (JP) 2022-03-24 US disclosed
US-20080194681-A1 Novel Inhibitors of Histone Deacetylase for the Treatment of Disease KALYPSYS, INC. (US) 2008-08-14 US disclosed
US-20080194681-A1 Novel Inhibitors of Histone Deacetylase for the Treatment of Disease KALYPSYS, INC. (US) 2008-08-14 US disclosed
US-20080194681-A1 Novel Inhibitors of Histone Deacetylase for the Treatment of Disease KALYPSYS, INC. (US) 2008-08-14 US disclosed
US-7374856-B2 Positive type photo-sensitive siloxane composition, cured film formed from the composition and device incorporating the cured film TORAY INDUSTRIES, INC. (JP) 2008-05-20 US disclosed
EP-1819669-A2 NOVEL INHIBITORS OF HISTONE DEACETYLASE FOR THE TREATMENT OF DISEASE Kalypsys, Inc. (US) 2007-08-22 EP disclosed
WO-2006063294-A2 NOVEL INHIBITORS OF HISTONE DEACETYLASE FOR THE TREATMENT OF DISEASE KALYPSYS, INC. (US) 2006-06-15 WO disclosed
WO-2006063294-A2 NOVEL INHIBITORS OF HISTONE DEACETYLASE FOR THE TREATMENT OF DISEASE KALYPSYS, INC. (US) 2006-06-15 WO disclosed
CN-1782878-A Positive type photo-sensitive siloxane composition, cured film formed from the composition and device incorporating the cured film TORAY INDUSTRIES (JP) 2006-06-07 CN disclosed
US-20060115766-A1 Positive type photo-sensitive siloxane composition, cured film formed from the composition and device incorporating the cured film TORAY INDUSTRIES, INC. (JP) 2006-06-01 US disclosed
EP-1662322-A2 Positive type photo-sensitive siloxane composition, curing film formed by the composition and device with the curing film TORAY INDUSTRIES, INC. (JP) 2006-05-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12529144-B2 Composition, method of producing substrate, and polymer SCO2, AOC2, PUF60 LMNA 4560/4885MAPT 360/4885KDM4E 3053/4885
US-20080194681-A1 Novel Inhibitors of Histone Deacetylase for the Treatment of Disease HDAC1, HDAC10, HDAC6 LMNA 1567/4885MAPT 478/4885KDM4E 621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.