SCHEMBL7595587

SCHEMBL7595587

CC(=O)OC(=O)C=C(C)C

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
TSHR P16473 2/20 0.50
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALOX15 P16050 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30
PRKCA P17252 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL779266 0.88 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10TDP1ALOX15
SCHEMBL17783667 0.78 HSD17B10 (0.50) ALDH1A1TSHRHSD17B10TDP1ALOX15
SCHEMBL779267 0.76 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10TDP1ALOX15
SCHEMBL7848630 0.76 ALDH1A1 (0.43) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL7848633 0.76 ALDH1A1 (0.43) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL6825661 0.75 TSHR (0.35) ALDH1A1TSHRALOX15L3MBTL1KEAP1
SCHEMBL825979 0.75 ALDH1A1 (0.67) ALDH1A1TSHRHSD17B10TDP1KEAP1
SCHEMBL14152614 0.75 ALDH1A1 (0.67) ALDH1A1TSHRHSD17B10TDP1KEAP1
SCHEMBL230634 0.75 ALDH1A1 (0.67) ALDH1A1TSHRHSD17B10TDP1KEAP1
SCHEMBL3990084 0.74 TSHR (0.35) ALDH1A1TSHRALOX15KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867427-B1 Process for producing branched aldehydes KURARAY CO (JP) 2002-11-06 EP disclosed
US-5932761-A Process for producing branched aldehydes KURARAY CO., LTD. (JP) 1999-08-03 US disclosed
EP-0867427-A1 Process for producing branched aldehydes KURARAY CO., LTD. (JP) 1998-09-30 EP disclosed
US-3975445-A Novel polyene compounds and process therefor HOFFMANN-LA ROCHE INC. (US) 1976-08-17 US disclosed