Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 2/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088177 | 0.91 | ATM (0.39) | ITGA4ITGB7ATMMEN1LMNA | |
| SCHEMBL7601470 | 0.89 | AKT1 (0.42) | ITGA4ITGB7MAPTTDP1ATM | |
| SCHEMBL7666444 | 0.89 | ATM (0.40) | ITGA4ITGB7MAPTTDP1ATM | |
| SCHEMBL6429868 | 0.86 | PPARA (0.43) | MEN1LMNACYP3A4CYP2D6ALOX15 | |
| SCHEMBL7597534 | 0.85 | ITGA4 (0.52) | ITGA4ITGB7MAPTTDP1ATM | |
| SCHEMBL7597532 | 0.85 | ITGA4 (0.52) | ITGA4ITGB7MAPTTDP1ATM | |
| SCHEMBL8874523 | 0.85 | ITGA4 (0.40) | ITGA4ITGB7MAPTTDP1ATM | |
| SCHEMBL8335478 | 0.82 | ITGA4 (0.41) | ITGA4ITGB7MAPTTDP1CTSS | |
| SCHEMBL25798363 | 0.81 | ITGA4 (0.44) | ITGA4ITGB7MAPTTDP1ATM | |
| SCHEMBL8397586 | 0.81 | AKT1 (0.43) | ITGA4ITGB7ATMCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061956-B1 | MANGANESE CHELATES WITH HIGH RELAXIVITY IN SERUM | BRACCO SPA (IT) | 2002-12-11 | — | — | EP | disclosed |
| US-6403055-B1 | CARBOXYLATED POLYAMINE COMPOUND | DIBRA S.P.A. (IT) | 2002-06-11 | — | — | US | disclosed |
| US-6337064-B1 | USED AS CONTRAST AGENT IN MAGNETIC RESONANCE IMAGING, MEDICAL DIAGNOSIS | DIBRA S.P.A. (IT) | 2002-01-08 | — | — | US | disclosed |