Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 2/20 | 0.52 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NPR3 | P17342 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597534 | 1.00 | ITGA4 (0.52) | ITGA4ITGB7MAPTTDP1POLB | |
| SCHEMBL8103206 | 0.95 | ITGA4 (0.51) | ITGA4ITGB7MAPTTDP1POLB | |
| SCHEMBL8103203 | 0.95 | ITGA4 (0.51) | ITGA4ITGB7MAPTTDP1POLB | |
| SCHEMBL7595591 | 0.85 | ITGA4 (0.41) | ITGA4ITGB7MAPTTDP1POLB | |
| SCHEMBL7601470 | 0.84 | AKT1 (0.42) | ITGA4ITGB7MAPTTDP1POLB | |
| SCHEMBL7666444 | 0.84 | ATM (0.40) | ITGA4ITGB7MAPTTDP1POLB | |
| SCHEMBL8874523 | 0.80 | ITGA4 (0.40) | ITGA4ITGB7MAPTTDP1POLB | |
| SCHEMBL8335478 | 0.80 | ITGA4 (0.41) | ITGA4ITGB7MAPTTDP1CTSS | |
| SCHEMBL15876048 | 0.80 | ITGA4 (0.61) | ITGA4ITGB7MAPTTDP1POLB | |
| SCHEMBL6428127 | 0.79 | ITGA4 (0.62) | ITGA4ITGB7MAPTTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061956-B1 | MANGANESE CHELATES WITH HIGH RELAXIVITY IN SERUM | BRACCO SPA (IT) | 2002-12-11 | — | — | EP | disclosed |
| US-6337064-B1 | USED AS CONTRAST AGENT IN MAGNETIC RESONANCE IMAGING, MEDICAL DIAGNOSIS | DIBRA S.P.A. (IT) | 2002-01-08 | — | — | US | disclosed |