Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1335837 | 0.83 | L3MBTL1 (0.60) | L3MBTL1ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL8261357 | 0.83 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL5290793 | 0.82 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1SMN1; SMN2LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL8760435 | 0.82 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL13343071 | 0.82 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL3180569 | 0.81 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL4205499 | 0.81 | KDM4E (0.58) | L3MBTL1ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL27995184 | 0.79 | KDM4E (0.44) | L3MBTL1ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL38651998 | 0.79 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL27856917 | 0.79 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1SMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714144-B2 | 5-chloro-1,3-dimethyl-1H-pyrazole-4-carbonyl chloride are initially charged in polyethylene glycol dimethyl ether, potassium fluoride and tetraphenylphosphonium bromide as phase tranfer catalyst and sulfolane to produce 5-fluoro-1,3-dimethyl-1H-pyrazole-4-carbonyl fluoride | BAYER CROPSCIENCE AG (DE) | 2010-05-11 | — | — | US | claimed |
| US-20090306401-A1 | Method For The Production of 5-Fluoro-1,3-Dialkyl-1H-Pyrazol-4-Carbonyl Fluorides | BAYER CROPSCIENCE AG (DE) | 2009-12-10 | — | — | US | claimed |
| EP-1928839-B1 | METHOD FOR THE PRODUCTION OF 5-FLUORO-1,3-DIALKYL-1H-PYRAZOL-4-CARBONYL FLUORIDES | BAYER CROPSCIENCE AG (DE) | 2008-12-31 | — | — | EP | claimed |
| EP-0776889-B1 | Process for the production of 1,3-dimethyl-5-fluoro-pyrazol-4-carboxanilides | BAYER AG (DE) | 2002-03-06 | — | — | EP | claimed |
| US-5675016-A | Process for the preparation of 1,3-dimethyl-5-fluoro-pyrazole-4-carboxanilides | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-07 | — | — | US | claimed |
| JP-2131481-A | — | — | None | — | — | JP | disclosed |
| JP-9176126-A | — | — | None | — | — | JP | disclosed |
| CN-111285807-B | Pyrazole amide compound and application thereof | 沈阳中化农药化工研发有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-110903279-B | Pyrazole compound, salt and application thereof | 潍坊中农联合化工有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-112390727-B | Oxime carboxylate compound and application thereof | 沈阳中化农药化工研发有限公司 | 2021-12-07 | — | — | CN | disclosed |
| CN-112390725-B | Preparation method of amide compound | 沈阳中化农药化工研发有限公司 | 2021-10-29 | — | — | CN | disclosed |
| WO-2021031984-A1 | CARBOXYLIC ACID OXIME ESTER COMPOUND AND USE THEREOF | 沈阳中化农药化工研发有限公司 | 2021-02-25 | — | — | WO | disclosed |
| EP-0368749-B1 | Substituted carboxylic acid, and their production and use | SUMITOMO CHEMICAL CO (JP) | 1994-01-05 | — | — | EP | disclosed |
| EP-0315502-B1 | SUBSTITUTED CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND AGRICULTURAL OR HORTICULTURAL FUNGICIDES CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-5049575-A | Substituted carboxylic acid, fungicidal compositions and use | SUMITOMO CHEMICAL COMPANY (JP) | 1991-09-17 | — | — | US | disclosed |
| US-5004816-A | Aminopyrrole intermediates for fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-04-02 | — | — | US | disclosed |
| JP-H02131481-A | SUBSTITUTED PYRAZOLECARBOXYLIC ACID DERIVATIVE, PRODUCTION THEREOF AND AGRICULTURAL AND HORTICULTURAL GERMICIDE AND INTERMEDIATE CONTAINING THE SAME AS ACTIVE INGREDIENT | SUMITOMO CHEM CO LTD | 1990-05-21 | — | — | JP | disclosed |
| EP-0368749-A1 | Substituted carboxylic acid, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-05-16 | — | — | EP | disclosed |
| US-4877441-A | 4-ACETAMINOPHTHALIDES | SUMITOMO CHEMICAL COMPANY LTD. (JP) | 1989-10-31 | — | — | US | disclosed |
| EP-0315502-A1 | Substituted carboxylic acid derivatives, processes for preparing the same and agricultural or horticultural fungicides containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306401-A1 | Method For The Production of 5-Fluoro-1,3-Dialkyl-1H-Pyrazol-4-Carbonyl Fluorides | CYP4X1, DHX35, AOX1 | L3MBTL1 3674/4885ALDH1A1 155/4885SMN1; SMN2 3846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.