SCHEMBL1335837

SCHEMBL1335837

Cc1nn(C)c(Cl)c1C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.60
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
KDM4E B2RXH2 3/20 0.51
MAPT P10636 1/20 0.51
ALDH1A1 P00352 3/20 0.50
LMNA P02545 2/20 0.47
GAA P10253 2/20 0.46
SMN1; SMN2 Q16637 3/20 0.43
POLB P06746 1/20 0.41
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8760435 0.98 L3MBTL1 (0.58) L3MBTL1MEN1KMT2AKDM4EMAPT
SCHEMBL38651998 0.86 L3MBTL1 (0.51) L3MBTL1MEN1KMT2AKDM4EMAPT
SCHEMBL759605 0.83 L3MBTL1 (0.56) L3MBTL1MEN1KMT2AKDM4EMAPT
SCHEMBL8261357 0.83 L3MBTL1 (0.56) L3MBTL1MEN1KMT2AKDM4EMAPT
SCHEMBL5290793 0.82 L3MBTL1 (0.54) L3MBTL1MEN1KMT2AKDM4EMAPT
SCHEMBL13343071 0.82 L3MBTL1 (0.54) L3MBTL1MEN1KMT2AKDM4EMAPT
SCHEMBL8306711 0.81 L3MBTL1 (0.49) L3MBTL1MEN1KMT2AKDM4EMAPT
SCHEMBL30984209 0.79 L3MBTL1 (0.44) L3MBTL1MEN1KMT2AKDM4EMAPT
Hydrochloric Acid SCHEMBL3180576 0.79 L3MBTL1 (0.47) L3MBTL1MEN1KMT2AKDM4EMAPT
SCHEMBL27856917 0.79 L3MBTL1 (0.55) L3MBTL1MEN1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2200440-B1 ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS CRESTONE INC (US) 2017-07-19 EP claimed
CN-102083827-A Thiazolidine compounds as orexin receptor antagonists ACTELION PHARMACEUTICALS LTD 2011-06-01 CN claimed
US-20110105491-A1 THIAZOLIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS ACTELION PHARMACEUTICALS LTD. (CH) 2011-05-05 US claimed
EP-2079690-B1 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES ACTELION PHARMACEUTICALS LTD (CH) 2010-09-15 EP claimed
EP-2200440-A1 ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS Crestone, Inc. (US) 2010-06-30 EP claimed
WO-2010038200-A1 OXAZOLIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS ACTELION PHARMACEUTICALS LTD (CH) 2010-04-08 WO claimed
US-20100016401-A1 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES Actelion Phamaceuticals Ltd. (CH) 2010-01-21 US claimed
WO-2010004507-A1 THIAZOLIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS ACTELION PHARMACEUTICALS LTD (CH) 2010-01-14 WO claimed
CN-101522618-A 3-aza-bicyclo[3.1.0]hexane derivatives ACTELION PHARMACEUTICALS LTD (CH) 2009-09-02 CN claimed
EP-2079690-A2 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES Actelion Pharmaceuticals Ltd. (CH) 2009-07-22 EP claimed
CN-101405270-A Pyrazoles as 11-beta-HSD-1 HOFFMANN LA ROCHE (CH) 2009-04-08 CN claimed
WO-2009015208-A1 ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS REPLIDYNE, INC. (US) 2009-01-29 WO claimed
WO-2008038251-A2 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES ACTELION PHARMACEUTICALS LTD (CH) 2008-04-03 WO claimed
EP-1902025-A1 KINASE INHIBITORS Allergan, Inc. (US) 2008-03-26 EP claimed
US-20070032478-A1 Kinase Inhibitors ALLERGAN, INC. 2007-02-08 US claimed
WO-2007008895-A1 KINASE INHIBITORS ALLERGAN, INC. (US) 2007-01-18 WO claimed
CN-122004231-A Comprising an oxa carfentrazone-ethyl herbicide composition and application thereof 山东滨农科技有限公司 2026-05-12 CN disclosed
CN-122004230-A Comprising an oxa carfentrazone-ethyl herbicide composition and application thereof 山东滨农科技有限公司 2026-05-12 CN disclosed
CN-1015107-B Process for producing pyrimidine or triazine derivative TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1991-12-18 CN disclosed
CN-86107113-A Herbicidal compounds, process for their preparation and their use 1987-05-27 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110105491-A1 THIAZOLIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS HCRTR2, HCRTR1, OXTR L3MBTL1 3789/4885MEN1 659/4885KMT2A 1736/4885
US-20100016401-A1 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES HCRTR1, HCRTR2, CNR1 L3MBTL1 4253/4885MEN1 956/4885KMT2A 1003/4885
US-20070032478-A1 Kinase Inhibitors ABL1, LCK, ERBB2 L3MBTL1 2164/4885MEN1 2293/4885KMT2A 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.