Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.58 |
| ▸ | STS | P08842 | 7/20 | 0.50 |
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10809867 | 0.81 | SHBG (0.52) | SHBGSTSESR1ESR2KDM4E | |
| SCHEMBL13725675 | 0.80 | SHBG (0.70) | SHBGSTSESR1ESR2MEN1 | |
| SCHEMBL975788 | 0.80 | SHBG (0.70) | SHBGSTSESR1ESR2MEN1 | |
| SCHEMBL30887214 | 0.80 | SHBG (0.70) | SHBGSTSESR1ESR2MEN1 | |
| SCHEMBL11096655 | 0.80 | SHBG (0.70) | SHBGSTSESR1ESR2MEN1 | |
| SCHEMBL29446097 | 0.80 | SHBG (0.70) | SHBGSTSESR1ESR2MEN1 | |
| SCHEMBL8509057 | 0.79 | STS (0.66) | SHBGSTSESR1ESR2KDM4E | |
| SCHEMBL23645783 | 0.77 | SHBG (0.53) | SHBGSTSESR1ESR2KDM4E | |
| SCHEMBL14048673 | 0.77 | SHBG (0.50) | SHBGSTSESR1ESR2KDM4E | |
| SCHEMBL17525967 | 0.77 | SHBG (0.53) | SHBGSTSESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986573-B1 | NON-ESTROGENIC ESTRADIOL DERIVATIVES WITH AN ANTIOXIDANT EFFECT | JENAPHARM GMBH (DE) | 2002-10-09 | — | — | EP | disclosed |