Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
| ▸ | STS | P08842 | 8/20 | 0.44 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14048707 | 0.87 | SHBG (0.49) | SHBGSTSESR1ESR2KDM4E | |
| SCHEMBL14048674 | 0.87 | SHBG (0.52) | SHBGSTSESR1ESR2KDM4E | |
| SCHEMBL17525967 | 0.84 | SHBG (0.53) | SHBGSTSESR1ESR2KDM4E | |
| SCHEMBL13952055 | 0.82 | STS (0.61) | SHBGSTSESR1ESR2LMNA | |
| SCHEMBL13951889 | 0.79 | STS (0.69) | SHBGSTSESR1ESR2LMNA | |
| SCHEMBL7596151 | 0.77 | SHBG (0.58) | SHBGSTSESR1ESR2KDM4E | |
| SCHEMBL17525955 | 0.76 | ESR1 (0.47) | STSESR1ESR2KDM4EMEN1 | |
| SCHEMBL13952052 | 0.75 | STS (0.50) | SHBGSTSESR1ESR2KDM4E | |
| SCHEMBL14048668 | 0.73 | STS (0.51) | SHBGSTSESR1ESR2KDM4E | |
| SCHEMBL17525944 | 0.73 | SHBG (0.70) | SHBGSTSESR1ESR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124922-A1 | 17ALPHA-SUBSTITUTED STEROIDS AS SYSTEMIC ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS | ENDORECHERCHE, INC. (CA) | 2008-10-23 | — | — | WO | disclosed |