Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318268 | 0.83 | NPC1 (0.83) | NPC1RAB9ATDP1ALOX15CYP3A4 | |
| SCHEMBL9781542 | 0.83 | NPC1 (0.63) | NPC1RAB9ATDP1ALOX15CYP3A4 | |
| SCHEMBL6522420 | 0.83 | NPC1 (0.83) | NPC1RAB9ATDP1ALOX15CYP3A4 | |
| SCHEMBL11261432 | 0.79 | ALOX15 (0.48) | NPC1RAB9ATDP1ALOX15CYP3A4 | |
| SCHEMBL27858583 | 0.79 | NPC1 (0.59) | NPC1RAB9ATDP1ALOX15CYP3A4 | |
| SCHEMBL8920417 | 0.78 | CASP1 (0.48) | NPC1RAB9ATDP1CYP3A4TP53 | |
| SCHEMBL11611736 | 0.76 | NPC1 (0.41) | NPC1RAB9AALOX15ALDH1A1HSD17B10 | |
| SCHEMBL28716249 | 0.76 | NPC1 (0.41) | NPC1RAB9ATDP1ALOX15CYP3A4 | |
| SCHEMBL810664 | 0.76 | ALDH1A1 (0.59) | NPC1RAB9ATDP1ALOX15CYP3A4 | |
| SCHEMBL735441 | 0.75 | HSD17B10 (0.44) | NPC1RAB9ATDP1ALOX15CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109134267-B | Synthetic method of aromatic amine compound | 北京大学 | 2020-11-17 | — | — | CN | disclosed |
| CN-109134267-A | A kind of synthetic method of aromatic amine compounds | 北京大学 | 2019-01-04 | — | — | CN | disclosed |
| EP-0900023-B1 | SUBSTITUTED AMINOMETHYL PHENYL SULPHONYL UREAS, THEIR PRODUCTION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE GMBH (DE) | 2002-11-27 | — | — | EP | disclosed |
| US-5925596-A | PRE-EMERGENCE AND POST-EMERGENCE HERBICIDES | HOECHST-SCHERING AGREVO GMBH (DE) | 1999-07-20 | — | — | US | disclosed |
| EP-0900023-A1 | SUBSTITUTED AMINOMETHYL PHENYL SULPHONYL UREAS, THEIR PRODUCTION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | Hoechst Schering AgrEvo GmbH (DE) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997040690-A1 | SUBSTITUTED AMINOMETHYL PHENYL SULPHONYL UREAS, THEIR PRODUCTION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1997-11-06 | — | — | WO | disclosed |