Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.39 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | CA3 | P07451 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28690872 | 0.89 | CDK1 (0.43) | HPGDPOLBHTTALDH1A1KDM4E | |
| SCHEMBL10717968 | 0.81 | KDM4E (0.36) | HTTKDM4ECYP1A2CYP2C9MEN1 | |
| SCHEMBL13906690 | 0.78 | TTR (0.39) | HPGDALDH1A1KDM4EMAPTCYP1A2 | |
| SCHEMBL3398797 | 0.78 | HPGD (0.37) | HPGDPOLBHTTALDH1A1KDM4E | |
| SCHEMBL7047230 | 0.75 | LMNA (0.51) | HPGDALDH1A1KDM4EMAP2K1MAP2K2 | |
| SCHEMBL9548344 | 0.75 | ALDH1A1 (0.40) | HPGDPOLBHTTALDH1A1KDM4E | |
| SCHEMBL27106134 | 0.75 | MEN1 (0.36) | HPGDALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8858998 | 0.74 | ALDH1A1 (0.40) | HPGDPOLBHTTALDH1A1KDM4E | |
| SCHEMBL11178469 | 0.74 | ALDH1A1 (0.36) | HPGDPOLBHTTALDH1A1KDM4E | |
| SCHEMBL11290559 | 0.74 | ALDH1A1 (0.40) | HPGDPOLBHTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448442-B1 | X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2002-09-10 | — | — | US | disclosed |