Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL4766825 | 0.91 | SMN1; SMN2 (0.40) | CYP2D6CNR1CNR2ALDH1A1LMNA | |
| SCHEMBL7596756 | 0.87 | CYP2D6 (0.39) | CYP2D6CNR1CNR2ALDH1A1LMNA | |
| SCHEMBL4772828 | 0.86 | SMN1; SMN2 (0.41) | CYP2D6CNR1CNR2LMNASMN1; SMN2 | |
| SCHEMBL7778367 | 0.81 | CYP2D6 (0.44) | CYP2D6CNR1CNR2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7775757 | 0.80 | CYP2D6 (0.44) | CYP2D6CNR1CNR2ALDH1A1LMNA | |
| Oxalic Acid SCHEMBL6292417 | 0.79 | SMN1; SMN2 (0.41) | CYP2D6CNR1CNR2ALDH1A1LMNA | |
| Oxalic Acid SCHEMBL7590835 | 0.79 | CYP2D6 (0.41) | CYP2D6CNR1CNR2ALDH1A1LMNA | |
| SCHEMBL4772807 | 0.78 | SMN1; SMN2 (0.41) | CYP2D6CNR1CNR2ALDH1A1LMNA | |
| Oxalic Acid SCHEMBL4793136 | 0.78 | DHODH (0.41) | CYP2D6CNR1CNR2ALDH1A1LMNA | |
| Oxalic Acid SCHEMBL4772488 | 0.78 | KMT2A (0.41) | CYP2D6CNR1CNR2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020013460-A1 | Condensed pyridine compound | EISAI CO., LTD | 2002-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013460-A1 | Condensed pyridine compound | MUSK, HTR1A, PAX3 | CYP2D6 3573/4885CNR1 475/4885CNR2 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.