Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | NPY1R | P25929 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | NPY2R | P49146 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | IDH2 | P48735 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrogen SCHEMBL7553013 | 0.95 | KCNMA1 (0.64) | KCNMA1HDAC1HDAC8HDAC6POLB | |
| SCHEMBL22075849 | 0.90 | POLB (0.69) | KCNMA1POLBHPGDSMN1; SMN2LMNA | |
| SCHEMBL11819922 | 0.87 | MAPT (0.68) | KCNMA1POLBHPGDSMN1; SMN2MAPT | |
| SCHEMBL11166422 | 0.86 | EPHX1 (0.76) | GAAMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL3793263 | 0.85 | KCNMA1 (0.76) | KCNMA1LMNAMAPTKDM4ENPC1 | |
| SCHEMBL25080518 | 0.84 | POLB (0.57) | POLBSMN1; SMN2LMNAGAAMAPT | |
| SCHEMBL31471694 | 0.84 | POLB (0.61) | HDAC1POLBHPGDSMN1; SMN2LMNA | |
| SCHEMBL11305759 | 0.84 | POLB (0.61) | HDAC1POLBHPGDSMN1; SMN2LMNA | |
| SCHEMBL19976953 | 0.83 | LMNA (0.56) | KCNMA1HDAC1HDAC8HDAC6POLB | |
| SCHEMBL5310996 | 0.83 | KCNMA1 (0.73) | KCNMA1HDAC1HDAC8HDAC6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002066092-A2 | DRUG ELUTING DEVICE FOR TREATING VASCULAR DISEASES | ANGIOGENE INC. (CA) | 2002-08-29 | — | — | WO | claimed |
| WO-2017197088-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS FOR THE TREATMENT OF INFLAMMATORY CONDITIONS | PHARMAKEA, INC. (US) | 2017-11-16 | — | — | WO | disclosed |