Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | IDH2 | P48735 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976968 | 0.86 | KCNMA1 (0.57) | LMNAMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL19976911 | 0.85 | LMNA (0.54) | LMNAMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL19976951 | 0.85 | HDAC1 (0.51) | LMNAMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL19976950 | 0.85 | ALDH1A1 (0.51) | LMNAMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL19976922 | 0.84 | HPGD (0.66) | LMNAALDH1A1SMN1; SMN2GAAPOLB | |
| SCHEMBL7596928 | 0.83 | KCNMA1 (0.69) | LMNAMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL19977031 | 0.83 | KCNMA1 (0.54) | LMNAMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL16999317 | 0.82 | CTSL (0.57) | — | |
| SCHEMBL19976948 | 0.81 | KMT2A (0.58) | LMNAMEN1KMT2ANPSR1ALDH1A1 | |
| Nitrogen SCHEMBL7553013 | 0.80 | KCNMA1 (0.64) | LMNAMEN1KMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102193-B1 | ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES | UNIV RUTGERS (US) | 2023-01-11 | — | — | EP | disclosed |
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |