Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7596934 | 1.00 | RORC (0.44) | RORCACHEBCHEBACE1ALDH1A1 | |
| SCHEMBL4602297 | 0.90 | ACHE (0.46) | ACHECHRM2CHRM3LMNA | |
| SCHEMBL6043648 | 0.86 | ACHE (0.42) | ACHEBCHEBACE1MAPK1 | |
| SCHEMBL6043641 | 0.86 | ACHE (0.42) | ACHEBCHEBACE1MAPK1 | |
| SCHEMBL27502934 | 0.83 | RORC (0.41) | RORCACHEBCHEBACE1ALDH1A1 | |
| SCHEMBL6041242 | 0.82 | ALDH1A1 (0.45) | RORCACHEBCHEBACE1ALDH1A1 | |
| SCHEMBL6041243 | 0.82 | ALDH1A1 (0.45) | RORCACHEBCHEBACE1ALDH1A1 | |
| SCHEMBL6043311 | 0.81 | RORC (0.40) | RORCACHEBCHEBACE1ALDH1A1 | |
| SCHEMBL6043305 | 0.81 | RORC (0.40) | RORCACHEBCHEBACE1ALDH1A1 | |
| SCHEMBL7138824 | 0.76 | ALDH1A1 (0.47) | ACHEBCHEALDH1A1HPGDCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |