Bifenox

Bifenox

SCHEMBL7597188

COC(=O)c1cc(Oc2ccc(Cl)cc2Cl)ccc1[N+](=O)[O-].COc1cc(OC)nc(NC(=O)NS(=O)(=O)N(C)S(C)(=O)=O)n1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.62
GAA P10253 1/20 0.39
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
TTR P02766 1/20 0.38
PPOX P50336 1/20 0.38
TBXA2R P21731 3/20 0.36
CDK1 P06493 1/20 0.36
MAPT P10636 2/20 0.36
LMNA P02545 2/20 0.36
ALDH1A1 P00352 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36
MAPK1 P28482 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
G6PD P11413 1/20 0.34
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bifenox SCHEMBL7595826 0.87 TDP1 (0.47) TDP1GAAKMT2AMEN1TTR
Acifluorfen SCHEMBL7593293 0.85 TDP1 (0.60) TDP1GAAKMT2AMEN1TTR
Nicosulfuron SCHEMBL7582294 0.85 TDP1 (0.54) TDP1GAAKMT2AMEN1TTR
Flupyrsulfuron SCHEMBL7580925 0.84 TDP1 (0.55) TDP1GAAKMT2AMEN1TTR
Fomesafen SCHEMBL7593914 0.84 TDP1 (0.51) TDP1GAAKMT2AMEN1TTR
Bifenox SCHEMBL7577737 0.83 TDP1 (0.55) TDP1GAAKMT2AMEN1TTR
Halosulfuron SCHEMBL7576853 0.83 TDP1 (0.55) TDP1GAAKMT2AMEN1TTR
Ethoxysulfuron SCHEMBL7584739 0.83 TDP1 (0.56) TDP1GAAKMT2AMEN1TTR
Bifenox SCHEMBL7579509 0.83 TDP1 (0.56) TDP1GAAKMT2AMEN1TTR
SCHEMBL7591401 0.82 KMT2A (0.46) TDP1GAAKMT2AMEN1TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885GAA 288/4885KMT2A 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.