Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9392486 | 0.92 | CCKBR (0.60) | CCKBRCCKAR | |
| SCHEMBL8401920 | 0.86 | CCKBR (0.47) | CCKBRCCKAR | |
| SCHEMBL8095731 | 0.81 | CCKBR (0.46) | CCKBRCCKAR | |
| SCHEMBL8081919 | 0.80 | NPY1R (0.51) | CCKBR | |
| SCHEMBL8093420 | 0.80 | CCKBR (0.45) | CCKBRCCKAR | |
| SCHEMBL8089866 | 0.80 | CCKBR (0.41) | CCKBRCCKAR | |
| SCHEMBL8401847 | 0.79 | CCKBR (0.44) | CCKBRCCKAR | |
| SCHEMBL7753002 | 0.76 | CCKBR (0.37) | CCKBRCCKAR | |
| SCHEMBL7752996 | 0.74 | CCKBR (0.47) | CCKBRCCKAR | |
| SCHEMBL23777550 | 0.73 | CCKAR (1.00) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0694039-B1 | 1,5-BENZODIAZEPINE DERIVATIVES HAVING CCK ANTAGONISTIC AND OR AGONISTIC ACTIVITY | GLAXO WELLCOME INC (US) | 2001-01-24 | — | — | EP | claimed |
| EP-1212305-A2 | 1,5-BENZODIAZEPINE DERIVATIVES AS CCK-A RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2002-06-12 | — | — | EP | disclosed |
| WO-2000068209-A2 | 1,5-BENZODIAZEPINE DERIVATIVES AS CCK-A RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2000-11-16 | — | — | WO | disclosed |
| US-5646140-A | CHOLECYSTOKININ ANTAGONIST; APETITE CONTROL | GLAXO WELLCOME INC. (US) | 1997-07-08 | — | — | US | disclosed |