Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 15/20 | 0.46 |
| ▸ | CCKAR | P32238 | 2/20 | 0.41 |
| ▸ | NPY1R | P25929 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081919 | 0.86 | NPY1R (0.51) | CCKBRNPY1R | |
| SCHEMBL8089866 | 0.85 | CCKBR (0.41) | CCKBRCCKARNPY1RALDH1A1 | |
| SCHEMBL7597322 | 0.81 | CCKBR (0.58) | CCKBRCCKAR | |
| SCHEMBL6906918 | 0.75 | AADAT (0.36) | ALDH1A1 | |
| SCHEMBL8095729 | 0.75 | CCKAR (0.67) | CCKBRCCKARALDH1A1 | |
| SCHEMBL8093420 | 0.74 | CCKBR (0.45) | CCKBRCCKAR | |
| SCHEMBL9392486 | 0.73 | CCKBR (0.60) | CCKBRCCKAR | |
| SCHEMBL8081891 | 0.73 | ALDH1A1 (0.38) | CCKBRALDH1A1 | |
| SCHEMBL8089877 | 0.72 | ALDH1A1 (0.39) | CCKBRCCKARALDH1A1 | |
| SCHEMBL8401920 | 0.71 | CCKBR (0.47) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096885-A | EXHIBIT AGONIST ACTIVITY FOR CCK-A RECEPTORS THEREBY ENABLING THEM TO MODULATE THE HORMONES GASTRIN AND CHOLECYSTOKININ IN MAMMALS. | GLAXO WELLCOME INC. (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0785944-A1 | ACYL AMINO ACETAMIDE DERIVATIVES WITH AGONIST ACTIVITY FOR CCK-A RECEPTORS | GLAXO WELLCOME INC. (US) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011940-A1 | ACYL AMINO ACETAMIDE DERIVATIVES WITH AGONIST ACTIVITY FOR CCK-A RECEPTORS | GLAXO WELLCOME INC. (US) | 1996-04-25 | — | — | WO | disclosed |