SCHEMBL7597344

SCHEMBL7597344

C=CCOC(=O)Nn1cnc2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.54
ALOX15 P16050 1/20 0.54
CYP3A4 P08684 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C19 P33261 1/20 0.50
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA3 P07451 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA13 Q8N1Q1 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
FGFR1 P11362 2/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8419574 0.82 CYP1A2 (0.60) HSD17B10ALOX15CYP3A4CYP1A2CYP2D6
SCHEMBL1685055 0.80 HSD17B10 (0.61) HSD17B10ALOX15CYP3A4CYP1A2CYP2D6
SCHEMBL11844044 0.77 ALOX15 (0.55) HSD17B10ALOX15CYP3A4CYP1A2CYP2D6
SCHEMBL9791261 0.77 ASAH1 (0.47) HSD17B10CYP3A4FGFR1NPC1EGLN3
SCHEMBL204727 0.74 ALOX15 (0.64) HSD17B10ALOX15CYP3A4CYP1A2CYP2D6
SCHEMBL707209 0.72 ALOX15 (0.58) HSD17B10ALOX15CYP3A4CYP1A2CYP2D6
SCHEMBL6954737 0.72 ALOX15 (0.58) HSD17B10ALOX15CYP3A4CYP1A2CYP2D6
SCHEMBL18991593 0.72 HSD17B10 (0.66) HSD17B10ALOX15CYP3A4CYP1A2CYP2D6
SCHEMBL1062170 0.71 TDP1 (0.44) HSD17B10ALOX15CYP3A4CYP1A2CYP2D6
SCHEMBL11845978 0.71 ALOX15 (0.53) HSD17B10ALOX15CYP3A4CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0933191-B1 Article based on vegetable fibers, suitable for the manufacture of vehicle parts VISTEON SYSTEMES INTERIEURS S (FR) 2002-07-10 EP claimed
EP-0014443-B1 DILUTABLE ALKYL-BENZIMIDAZOLECARBAMATE FORMULATION, PROCESS FOR ITS PREPARATION AND ITS USE AS BIOCIDE RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1982-11-03 EP claimed
EP-0016857-B1 MICROBICIDAL AGENT AND APPLICATION THEREOF BAYER AG (DE) 1982-06-09 EP claimed
JP-3263472-A None JP disclosed
CN-1094539-C Antibacterial softener composition KAO CORP (JP) 2002-11-20 CN disclosed
CN-1151456-A Antibacterial softener composition KAO CORP (JP) 1997-06-11 CN disclosed
EP-0562878-B1 Room temperature curable organopolysiloxane composition and cured product of the same SHINETSU CHEMICAL CO (JP) 1997-05-14 EP disclosed
EP-0510838-B1 Room temperature curable organopolysiloxane composition having mildewproofing property SHINETSU CHEMICAL CO (JP) 1996-08-28 EP disclosed
US-5314981-A Fluoropolymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-05-24 US disclosed
US-5264484-A Room temperature curable organopolysiloxane composition having mildewproofing property SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-11-23 US disclosed
EP-0562878-A2 Room temperature curable organopolysiloxane composition and cured product of the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-09-29 EP disclosed
EP-0510838-A1 Room temperature curable organopolysiloxane composition having mildewproofing property SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-10-28 EP disclosed
JP-H03263472-A COATING MATERIAL FOR HEAT EXCHANGER OF AIR-CONDITIONER AND HEAT EXCHANGER COATED THEREWITH TAKEDA CHEM IND LTD 1991-11-22 JP disclosed
EP-0014443-A1 Dilutable alkyl-benzimidazolecarbamate formulation, process for its preparation and its use as biocide RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1980-08-20 EP disclosed
US-3897448-A Process for the manufacture of alkyl benzimidazolylcarbamates RHONE PROGIL 1975-07-29 US disclosed
US-3897448-A Process for the manufacture of alkyl benzimidazolylcarbamates RHONE PROGIL 1975-07-29 US disclosed