SCHEMBL8419574

SCHEMBL8419574

CCOC(=O)Nn1cnc2ccccc21

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.60
CYP3A4 P08684 1/20 0.60
CYP2D6 P10635 1/20 0.60
CYP2C19 P33261 1/20 0.60
ALOX15 P16050 1/20 0.58
HSD17B10 Q99714 1/20 0.58
KDM4E B2RXH2 4/20 0.47
ALDH1A1 P00352 1/20 0.47
GLA P06280 1/20 0.46
POLB P06746 1/20 0.46
ASAH1 Q13510 3/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NPC1 O15118 2/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA3 P07451 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1685055 0.86 HSD17B10 (0.61) CYP1A2CYP3A4CYP2D6CYP2C19ALOX15
SCHEMBL7597344 0.82 HSD17B10 (0.54) CYP1A2CYP3A4CYP2D6CYP2C19ALOX15
SCHEMBL18991593 0.81 HSD17B10 (0.66) CYP1A2CYP3A4CYP2D6CYP2C19ALOX15
SCHEMBL204727 0.80 ALOX15 (0.64) CYP1A2CYP3A4CYP2D6CYP2C19ALOX15
SCHEMBL6954737 0.79 ALOX15 (0.58) CYP1A2CYP3A4CYP2D6CYP2C19ALOX15
SCHEMBL5407957 0.77 LMNA (0.63) CYP1A2CYP3A4CYP2D6CYP2C19ALOX15
SCHEMBL6234447 0.77 ALOX15 (0.64) CYP1A2CYP3A4CYP2D6CYP2C19ALOX15
SCHEMBL29145104 0.76 ALDH1A1 (0.55) HSD17B10KDM4EALDH1A1ASAH1L3MBTL1
SCHEMBL707209 0.75 ALOX15 (0.58) CYP1A2CYP3A4CYP2D6CYP2C19ALOX15
SCHEMBL14527306 0.74 CYP4Z1 (0.50) CYP1A2KDM4EGLAPOLBASAH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11172157-A None JP disclosed
JP-7149609-A None JP disclosed
JP-H11172157-A ANTIFUNGAL AND ANTIMICROBIAL COATING MATERIAL SUNSTAR ENG INC 1999-06-29 JP disclosed
JP-H07149609-A ANTIMICROBIAL COMPOSITION AND PREPARATION THEREOF K I KASEI KK 1995-06-13 JP disclosed