SCHEMBL7597399

SCHEMBL7597399

COC(c1ccccc1)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.41
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
IDO1 P14902 3/20 0.36
TDO2 P48775 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
HTR7 P34969 1/20 0.34
HTR2B P41595 1/20 0.34
CHRM2 P08172 2/20 0.33
CHRM1 P11229 2/20 0.33
DRD1 P21728 2/20 0.33
DRD3 P35462 2/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
CHRM3 P20309 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9449677 0.80 PNMT (0.44) PNMTNPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL3157927 0.79 PNMT (0.46) PNMTNPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL4751826 0.77 IDO1 (0.37) IDO1TDO2SMN1; SMN2HTR2BCHRM2
SCHEMBL29067758 0.76 PNMT (0.44) PNMTNPC1RAB9AMEN1MAPT
SCHEMBL6675580 0.75 PNMT (0.49) PNMTNPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL29617348 0.75 PNMT (0.49) PNMTNPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL6672847 0.75 PNMT (0.49) PNMTNPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL3684777 0.74 PNMT (0.37) PNMTNPC1RAB9AIDO1TDO2
SCHEMBL6674901 0.74 PNMT (0.49) PNMTNPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL6557930 0.74 PNMT (0.47) PNMTNPC1RAB9ASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1473809-A Diethers suitable for use in the preparation of ziegler-natta catalysts ��������ϩ����������޹�˾ 2004-02-11 CN claimed
CN-1141285-A Diethers suitable for use in the preparation of ziegler-natta catalysts MONTELL NORTH AMERICA INC (US) 1997-01-29 CN claimed
EP-1260523-B1 CATALYST SYSTEM FOR POLYMERIZATION AND COPOLYMERIZATION OF OLEFINS CHINA PETROCHEMICAL CORP (CN) 2013-01-23 EP disclosed
CN-1289451-C Diethers suitable for use in the preparation of ziegler-natta catalysts BASEL POLELEFINE ITALY S P A (IT) 2006-12-13 CN disclosed
CN-1210243-C Synthesis method of diether BASEL NORTH AMERICA CO LTD (US) 2005-07-13 CN disclosed
CN-1491929-A Diethers suitable for use in the preparation of ziegler-natta catalysts 2004-04-28 CN disclosed
CN-1473809-A Diethers suitable for use in the preparation of ziegler-natta catalysts ��������ϩ����������޹�˾ 2004-02-11 CN disclosed
CN-1121368-C Diethers suitable for use in the preparation of ziegler-natta catalysts MONTELL NORTH AMERICA INC (US) 2003-09-17 CN disclosed
EP-1260523-A1 CATALYST SYSTEM FOR POLYMERIZATION AND COPOLYMERIZATION OF OLEFINS CHINA PETROCHEMICAL CORPORATION (CN) 2002-11-27 EP disclosed
CN-1092670-C Process for producing solid catalyst component for olefin polymerization MONTELL NORTH AMERICA INC (US) 2002-10-16 CN disclosed
CN-1141285-A Diethers suitable for use in the preparation of ziegler-natta catalysts MONTELL NORTH AMERICA INC (US) 1997-01-29 CN disclosed
CN-1141303-A Process for producing solid catalyst component for olefin polymerization MONTELL NORTH AMERICA INC (US) 1997-01-29 CN disclosed