Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033927 | 0.82 | LMNA (0.67) | LMNARAB9ANPC1POLBHDAC6 | |
| SCHEMBL4789113 | 0.79 | ROCK2 (0.55) | LMNARAB9A | |
| SCHEMBL1528366 | 0.77 | NPC1 (0.74) | LMNARAB9AMAPTNPC1POLB | |
| SCHEMBL17046733 | 0.72 | LMNA (0.34) | LMNARAB9ANR1H4MAPTPOLB | |
| SCHEMBL12599743 | 0.72 | NR1H2 (0.58) | LMNARAB9ANPC1POLBHDAC6 | |
| SCHEMBL12402151 | 0.72 | HDAC3 (0.57) | LMNARAB9AMAPTNPC1POLB | |
| SCHEMBL17279681 | 0.72 | NR1H2 (0.58) | LMNARAB9ANPC1POLBHDAC6 | |
| SCHEMBL7597720 | 0.71 | SRD5A2 (0.41) | LMNARAB9ANR1H4MAPTNPC1 | |
| SCHEMBL7026348 | 0.70 | KDM4E (0.54) | LMNAHDAC6KDM4ESMN1; SMN2NR1H2 | |
| SCHEMBL23062798 | 0.70 | NPC1 (0.58) | LMNARAB9AMAPTNPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0919549-B1 | 3-(4-Tert-butylphenyl)-1H-1,2,4-trizaol-5-yl acetic acid and uses thereof, particularly for the preparation of photographic couplers | FUJI PHOTO FILM CO LTD (JP) | 2002-12-11 | — | — | EP | claimed |
| EP-0805150-B1 | A method for preparing 1H-1,2,4-triazol-5-yl acetic acid compounds, and the novel 3-(4-tert-butylphenyl)-1H-1,2,4-triazol-5-yl acetic acid | FUJI PHOTO FILM CO LTD (JP) | 2001-12-19 | — | — | EP | claimed |
| EP-0919549-A1 | 3-(4-Tert-butylphenyl)-1H-1,2,4-trizaol-5-yl acetic acid and uses thereof, particularly for the preparation of photographic couplers | FUJI PHOTO FILM CO., LTD. (JP) | 1999-06-02 | — | — | EP | claimed |
| EP-0805150-A2 | A method for preparing 1H-1,2,4-triazol-5-YL acetic compounds, and the novel 3-(4-tert-butylphenyl)-1H,2,4-triazol-5-yl acetic acid | Fuji Photo Film Co., Ltd. (JP) | 1997-11-05 | — | — | EP | claimed |
| CN-106366043-A | Intermediate of magenta coupler for colored photosensitive material and preparation method thereof | 富士胶片精细化学（无锡）有限公司 | 2017-02-01 | — | — | CN | disclosed |
| EP-0919549-B1 | 3-(4-Tert-butylphenyl)-1H-1,2,4-trizaol-5-yl acetic acid and uses thereof, particularly for the preparation of photographic couplers | FUJI PHOTO FILM CO LTD (JP) | 2002-12-11 | — | — | EP | disclosed |
| EP-0919549-B1 | 3-(4-Tert-butylphenyl)-1H-1,2,4-trizaol-5-yl acetic acid and uses thereof, particularly for the preparation of photographic couplers | FUJI PHOTO FILM CO LTD (JP) | 2002-12-11 | — | — | EP | disclosed |
| EP-0805150-B1 | A method for preparing 1H-1,2,4-triazol-5-yl acetic acid compounds, and the novel 3-(4-tert-butylphenyl)-1H-1,2,4-triazol-5-yl acetic acid | FUJI PHOTO FILM CO LTD (JP) | 2001-12-19 | — | — | EP | disclosed |
| EP-0805150-B1 | A method for preparing 1H-1,2,4-triazol-5-yl acetic acid compounds, and the novel 3-(4-tert-butylphenyl)-1H-1,2,4-triazol-5-yl acetic acid | FUJI PHOTO FILM CO LTD (JP) | 2001-12-19 | — | — | EP | disclosed |
| EP-0919549-A1 | 3-(4-Tert-butylphenyl)-1H-1,2,4-trizaol-5-yl acetic acid and uses thereof, particularly for the preparation of photographic couplers | FUJI PHOTO FILM CO., LTD. (JP) | 1999-06-02 | — | — | EP | disclosed |
| EP-0919549-A1 | 3-(4-Tert-butylphenyl)-1H-1,2,4-trizaol-5-yl acetic acid and uses thereof, particularly for the preparation of photographic couplers | FUJI PHOTO FILM CO., LTD. (JP) | 1999-06-02 | — | — | EP | disclosed |
| EP-0919549-A1 | 3-(4-Tert-butylphenyl)-1H-1,2,4-trizaol-5-yl acetic acid and uses thereof, particularly for the preparation of photographic couplers | FUJI PHOTO FILM CO., LTD. (JP) | 1999-06-02 | — | — | EP | disclosed |
| EP-0805150-A2 | A method for preparing 1H-1,2,4-triazol-5-YL acetic compounds, and the novel 3-(4-tert-butylphenyl)-1H,2,4-triazol-5-yl acetic acid | Fuji Photo Film Co., Ltd. (JP) | 1997-11-05 | — | — | EP | disclosed |