Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 11/20 | 0.39 |
| ▸ | CCKBR | P32239 | 4/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592838 | 0.85 | BDKRB1 (0.55) | BDKRB1CCKBRCCKAR | |
| SCHEMBL7593183 | 0.77 | BDKRB1 (0.61) | BDKRB1CCKBR | |
| SCHEMBL9008723 | 0.77 | BDKRB1 (0.54) | BDKRB1CCKBRCCKAR | |
| SCHEMBL9566076 | 0.75 | CCKBR (0.49) | BDKRB1CCKBRALDH1A1MAPTKDM4E | |
| SCHEMBL9008684 | 0.71 | BDKRB1 (0.45) | BDKRB1CCKBRCCKAR | |
| SCHEMBL9428816 | 0.67 | CCKBR (0.63) | BDKRB1CCKBRCCKAR | |
| SCHEMBL9008792 | 0.67 | CCKBR (0.45) | BDKRB1CCKBRCCKAR | |
| SCHEMBL9008683 | 0.67 | CCKBR (0.45) | BDKRB1CCKBRCCKAR | |
| SCHEMBL9008669 | 0.66 | BDKRB1 (0.40) | BDKRB1CCKBRCCKARMAPTKDM4E | |
| SCHEMBL9008659 | 0.66 | CCKBR (0.41) | BDKRB1CCKBRNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002099388-A2 | BENZODIAZEPINE BRADYKININ ANTAGONISTS | MERCK & CO., INC. (US) | 2002-12-12 | — | — | WO | disclosed |