Sugi Predict

Sugi Predict / Compounds / SCHEMBL7597660

SCHEMBL7597660

SCHEMBL7597660

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nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CTSS P25774 3/20 0.53
▸ CTSK P43235 3/20 0.53
▸ PSENEN Q9NZ42 1/20 0.45
▸ CA2 P00918 3/20 0.40
▸ CA1 P00915 1/20 0.38
▸ CA7 P43166 1/20 0.38
▸ KMT2A Q03164 1/20 0.37
▸ KDM4E B2RXH2 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3725796 0.91 CTSS (0.56) CTSSCTSKPSENENCA2CA1
SCHEMBL3725798 0.91 CTSS (0.56) CTSSCTSKPSENENCA2CA1
SCHEMBL7603103 0.88 CTSK (0.50) CTSSCTSKPSENENCA2CA1
SCHEMBL3737231 0.84 CTSK (0.58) CTSSCTSKPSENENCA2CA1
SCHEMBL3737229 0.84 CTSK (0.58) CTSSCTSKPSENENCA2CA1
SCHEMBL3728289 0.81 CTSK (0.51) CTSSCTSKPSENENCA2CA1
SCHEMBL3744201 0.81 CTSK (0.49) CTSSCTSKPSENENCA2CA1
SCHEMBL3744205 0.81 CTSK (0.49) CTSSCTSKPSENENCA2CA1
SCHEMBL8466501 0.81 CTSS (0.59) CTSSCTSKPSENENCA2CA1
SCHEMBL8466502 0.81 CTSS (0.59) CTSSCTSKPSENENCA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002503673-A — — 2002-02-05 — — JP claimed
EP-1054891-A1 PRODRUGS MEDIVIR AB (SE) 2000-11-29 — — EP claimed
WO-1999041275-A1 PRODRUGS MEDIVIR AB (SE) 1999-08-19 — — WO claimed