Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597660 | 0.88 | CTSS (0.53) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL3728289 | 0.87 | CTSK (0.51) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL18024826 | 0.86 | CTSK (0.50) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL1515310 | 0.82 | CTSK (0.54) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL16658566 | 0.82 | CTSK (0.54) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL3731939 | 0.81 | CTSK (0.52) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL14260540 | 0.81 | CTSK (0.52) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL3727156 | 0.81 | CTSK (0.52) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL8136019 | 0.81 | CTSK (0.47) | CTSKCTSSCA2CA1CA7 | |
| SCHEMBL17999705 | 0.79 | CTSK (0.54) | CTSKCTSSCA2CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002503673-A | — | — | 2002-02-05 | — | — | JP | claimed |
| EP-1054891-A1 | PRODRUGS | MEDIVIR AB (SE) | 2000-11-29 | — | — | EP | claimed |
| WO-1999041275-A1 | PRODRUGS | MEDIVIR AB (SE) | 1999-08-19 | — | — | WO | claimed |