Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | NPY1R | P25929 | 2/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597839 | 0.88 | FOLH1 (0.49) | FOLH1HTTSLC1A3SLC1A1LMNA | |
| SCHEMBL7595812 | 0.88 | FOLH1 (0.49) | FOLH1HTTSLC1A3SLC1A1LMNA | |
| SCHEMBL7595116 | 0.86 | FOLH1 (0.46) | FOLH1HTTSLC1A3SLC1A1LMNA | |
| SCHEMBL7597117 | 0.86 | FOLH1 (0.46) | FOLH1HTTSLC1A3SLC1A1LMNA | |
| SCHEMBL7600672 | 0.86 | FOLH1 (0.44) | FOLH1HTTSLC1A3SLC1A1LMNA | |
| SCHEMBL7601605 | 0.86 | FOLH1 (0.47) | FOLH1MMP2MMP9HTTSLC1A3 | |
| SCHEMBL7600359 | 0.85 | FOLH1 (0.45) | FOLH1MMP2MMP9HTTSLC1A3 | |
| SCHEMBL7600868 | 0.85 | FOLH1 (0.45) | FOLH1HTTSLC1A3SLC1A1LMNA | |
| SCHEMBL7600231 | 0.85 | FOLH1 (0.45) | FOLH1MMP2MMP9HTTSLC1A3 | |
| SCHEMBL7595138 | 0.85 | CYP2C9 (0.44) | UTS2RCYP2C9CYP2C19NPY1RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |