Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 2/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPY4R | P50391 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600989 | 0.92 | NPY1R (0.41) | KMT2AMEN1NPY1RNPY5RPOLB | |
| SCHEMBL7596845 | 0.90 | CNR2 (0.35) | KMT2AMEN1RAB9ASMN1; SMN2NPY1R | |
| SCHEMBL7596719 | 0.89 | CYP2C9 (0.48) | CYP2C9CYP2C19KMT2AMEN1RAB9A | |
| SCHEMBL7597057 | 0.89 | NPY4R (0.38) | NPY1RNPY2RNPY5RCNR1CNR2 | |
| SCHEMBL6898666 | 0.86 | CYP2C9 (0.45) | CYP2C9CYP2C19KMT2AMEN1RAB9A | |
| SCHEMBL7597835 | 0.85 | FOLH1 (0.42) | CYP2C9CYP2C19SMN1; SMN2NPY1RNPY2R | |
| SCHEMBL8059173 | 0.84 | CYP2C9 (0.44) | CYP2C9CYP2C19KMT2AMEN1RAB9A | |
| SCHEMBL7595802 | 0.82 | TRPM8 (0.41) | NPY1RCNR1CNR2 | |
| SCHEMBL7595142 | 0.82 | TRPM8 (0.41) | NPY1RCNR1CNR2 | |
| SCHEMBL7600642 | 0.81 | ITGB3 (0.36) | KMT2AMEN1NPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | claimed |
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |