Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479928 | 0.83 | POLB (0.51) | POLBMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7473046 | 0.81 | KMT2A (0.56) | POLBMAPTSMN1; SMN2KMT2AEPHX2 | |
| SCHEMBL7472773 | 0.78 | KMT2A (0.52) | POLBMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30761563 | 0.74 | KMT2A (0.55) | POLBMAPTSMN1; SMN2KMT2AEPHX2 | |
| SCHEMBL21436913 | 0.74 | KMT2A (0.55) | POLBMAPTSMN1; SMN2KMT2AEPHX2 | |
| SCHEMBL22639782 | 0.72 | P2RX7 (0.59) | POLBMAPTSMN1; SMN2KMT2AEPHX2 | |
| SCHEMBL8035779 | 0.71 | KMT2A (0.61) | SMN1; SMN2KMT2AEPHX2MEN1ALDH1A1 | |
| SCHEMBL3673650 | 0.69 | KMT2A (0.73) | SMN1; SMN2KMT2AEPHX2MEN1ALDH1A1 | |
| SCHEMBL9341104 | 0.69 | KMT2A (0.83) | SMN1; SMN2KMT2AEPHX2MEN1ALDH1A1 | |
| SCHEMBL31658991 | 0.69 | KMT2A (0.83) | SMN1; SMN2KMT2AEPHX2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861077-B1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2002-02-06 | — | — | EP | claimed |