Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473046 | 0.90 | KMT2A (0.56) | POLBMAPTSMN1; SMN2KMT2AEPHX2 | |
| SCHEMBL7472773 | 0.86 | KMT2A (0.52) | POLBMAPTSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL7597843 | 0.83 | POLB (0.46) | POLBMAPTSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL30761563 | 0.80 | KMT2A (0.55) | POLBMAPTSMN1; SMN2KMT2AEPHX2 | |
| SCHEMBL21436913 | 0.80 | KMT2A (0.55) | POLBMAPTSMN1; SMN2KMT2AEPHX2 | |
| SCHEMBL22639782 | 0.77 | P2RX7 (0.59) | POLBMAPTSMN1; SMN2KMT2AEPHX2 | |
| SCHEMBL8035779 | 0.75 | KMT2A (0.61) | SMN1; SMN2KMT2AEPHX2MEN1ALDH1A1 | |
| SCHEMBL3672285 | 0.75 | POLB (0.64) | POLBMAPTSMN1; SMN2KMT2AGRM4 | |
| SCHEMBL31658991 | 0.73 | KMT2A (0.83) | SMN1; SMN2KMT2AEPHX2MEN1ALDH1A1 | |
| SCHEMBL9341104 | 0.73 | KMT2A (0.83) | SMN1; SMN2KMT2AEPHX2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861077-B1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2002-02-06 | — | — | EP | claimed |
| EP-0861077-A4 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1999-03-03 | — | — | EP | claimed |
| EP-0861077-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-09-02 | — | — | EP | claimed |
| WO-1997017964-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-22 | — | — | WO | claimed |
| EP-0861077-B1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2002-02-06 | — | — | EP | disclosed |
| US-6107309-A | BLOOD DISORDERS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0861077-A4 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0861077-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997017964-A1 | HEMOREGULATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-22 | — | — | WO | disclosed |