Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | KIF11 | P52732 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL970721 | 0.75 | RPA1 (0.47) | NPC1RAB9ANOTUMPOLB | |
| SCHEMBL7854347 | 0.75 | METAP2 (0.42) | — | |
| SCHEMBL604349 | 0.74 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2POLBALOX15 | |
| SCHEMBL6680571 | 0.71 | NPC1 (0.72) | XDHNPC1RAB9AKIF11ALDH1A1 | |
| SCHEMBL12402151 | 0.70 | HDAC3 (0.57) | XDHNPC1RAB9AKIF11ALDH1A1 | |
| SCHEMBL1981034 | 0.70 | NOTUM (0.44) | NPC1RAB9AKIF11NOTUMPOLB | |
| SCHEMBL13871684 | 0.69 | NPC1 (0.69) | XDHNPC1RAB9AKIF11ALDH1A1 | |
| SCHEMBL4125159 | 0.69 | NPC1 (0.69) | XDHNPC1RAB9AKIF11ALDH1A1 | |
| SCHEMBL14062481 | 0.68 | NPC1 (0.54) | XDHNPC1RAB9AKIF11ALDH1A1 | |
| SCHEMBL3413673 | 0.68 | XDH (0.96) | XDHNPC1RAB9AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0919549-B1 | 3-(4-Tert-butylphenyl)-1H-1,2,4-trizaol-5-yl acetic acid and uses thereof, particularly for the preparation of photographic couplers | FUJI PHOTO FILM CO LTD (JP) | 2002-12-11 | — | — | EP | disclosed |
| EP-0805150-B1 | A method for preparing 1H-1,2,4-triazol-5-yl acetic acid compounds, and the novel 3-(4-tert-butylphenyl)-1H-1,2,4-triazol-5-yl acetic acid | FUJI PHOTO FILM CO LTD (JP) | 2001-12-19 | — | — | EP | disclosed |
| EP-0919549-A1 | 3-(4-Tert-butylphenyl)-1H-1,2,4-trizaol-5-yl acetic acid and uses thereof, particularly for the preparation of photographic couplers | FUJI PHOTO FILM CO., LTD. (JP) | 1999-06-02 | — | — | EP | disclosed |