Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.42 |
| ▸ | HPGDS | O60760 | 7/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL970721 | 0.78 | RPA1 (0.47) | NPC1RAB9ANR1H2NR1H3METAP2 | |
| SCHEMBL4827715 | 0.78 | ALDH1A1 (0.53) | SMN1; SMN2HPGDSALOX15IDO1METAP2 | |
| SCHEMBL10874362 | 0.77 | CYP1A2 (0.49) | NPC1RAB9ASMN1; SMN2IDO1METAP2 | |
| SCHEMBL7597983 | 0.74 | XDH (0.50) | NPC1RAB9ASMN1; SMN2ALOX15POLB | |
| SCHEMBL971896 | 0.72 | IDO1 (0.43) | NPC1RAB9AMAPK1NFKB1NFKB2 | |
| SCHEMBL1981034 | 0.70 | NOTUM (0.44) | NPC1RAB9APOLBADORA3L3MBTL1 | |
| SCHEMBL9322432 | 0.64 | RAB9A (0.50) | NPC1RAB9AMAPK1NFKB1NFKB2 | |
| SCHEMBL1870772 | 0.64 | L3MBTL1 (0.52) | NPC1RAB9AMAPK1NFKB1NFKB2 | |
| SCHEMBL371042 | 0.63 | L3MBTL1 (0.74) | NPC1RAB9AMAPK1NFKB1NFKB2 | |
| SCHEMBL3652642 | 0.63 | NPC1 (1.00) | NPC1RAB9AMAPK1NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100482416-C | Grinding fluid supply equipment of chemical mechanical grinding machine and grinding fluid mixing method | UNITED MICROELECTRONICS CORP (CN) | 2009-04-29 | — | — | CN | claimed |
| CN-1833821-A | Grinding fluid supply equipment of chemical mechanical grinding machine and grinding fluid mixing method | LIANHUA ELECTRONIC CO LTD (CN) | 2006-09-20 | — | — | CN | claimed |
| CN-114068833-A | Organometallic compound, light-emitting device including the same, and electronic apparatus | 三星显示有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-107074878-B | 2, 3-dihydro-thiazolo [3,2-a ] pyridin-5-one derivatives, intermediates thereof and their use as antibacterial agents | 快尔生物技术公司 | 2019-12-24 | — | — | CN | disclosed |
| US-10294244-B2 | 2,3-dihydro-thiazolo[3,2-A]pyridin-5-one derivatives, intermediates thereof, and their use as antibacterial agents | QURETECH BIO AB (SE) | 2019-05-21 | — | — | US | disclosed |
| US-10206401-B2 | Pyridine compounds for controlling invertebrate pests II | BASF SE (DE) | 2019-02-19 | — | — | US | disclosed |
| US-20180116221-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | BASF SE (DE) | 2018-05-03 | — | — | US | disclosed |
| US-20170334931-A1 | 2,3-Dihydro-Thiazolo[3,2-A]Pyridin-5-One Derivatives, Intermediates Thereof, and Their Use as Antibacterial Agents | QURETECH BIO AB (SE) | 2017-11-23 | — | — | US | disclosed |
| EP-3218382-A1 | 2,3-DIHYDRO-THIAZOLO[3,2-A]PYRIDIN-5-ONE DERIVATIVES, INTERMEDIATES THEREOF, AND THEIR USE AS ANTIBACERIAL AGENTS | Quretech Bio AB (SE) | 2017-09-20 | — | — | EP | disclosed |
| EP-2616458-B1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS II | BASF SE (DE) | 2016-07-20 | — | — | EP | disclosed |
| WO-2016075296-A1 | 2,3-DIHYDRO-THIAZOLO[3,2-A]PYRIDIN-5-ONE DERIVATIVES, INTERMEDIATES THEREOF, AND THEIR USE AS ANTIBACERIAL AGENTS | QURETECH BIO AB (SE) | 2016-05-19 | — | — | WO | disclosed |
| US-6642223-B2 | A benzoazepin or benzodiazepin derivatives, shows excellent anti-vasopressin activity, vasopressin agonistic activity and oxytocin antagonistic activity, and are useful as antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2003-11-04 | — | — | US | disclosed |
| EP-0765314-B1 | BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS | OTSUKA PHARMA CO LTD (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1221440-A1 | Benzoheterocyclic derivatives useful as vasopressin or oxytocin modulators | Otsuka Pharmaceutical Company, Limited (JP) | 2002-07-10 | — | — | EP | disclosed |
| US-20020049194-A1 | Benzoheterocyclic derivatives | OGAWA HIDENORI (JP) | 2002-04-25 | — | — | US | disclosed |
| US-6335327-B1 | Benzoheterocyclic derivatives | OTSUKA PHARMACEUTICALS CO., LTD. (JP) | 2002-01-01 | — | — | US | disclosed |
| US-6096735-A | Benzoheterocyclic derivatives | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5670526-A | ANTIINFLAMMATORY AGENT, IMMUNOSUPPRESSANT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| EP-0765314-A1 | BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-02 | — | — | EP | disclosed |
| WO-1995034540-A1 | BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10294244-B2 | 2,3-dihydro-thiazolo[3,2-A]pyridin-5-one derivatives, intermediates thereof, and their use as antibacterial agents | NOD1, MT-ND1, NDUFB7 | NPC1 1311/4885RAB9A 2588/4885MAPK1 871/4885 |
| US-20170334931-A1 | 2,3-Dihydro-Thiazolo[3,2-A]Pyridin-5-One Derivatives, Intermediates Thereof, and Their Use as Antibacterial Agents | NOD1, MT-ND1, NDUFB7 | NPC1 1311/4885RAB9A 2588/4885MAPK1 871/4885 |
| US-10206401-B2 | Pyridine compounds for controlling invertebrate pests II | PRXL2A, NR2C2, SHROOM3 | NPC1 4357/4885RAB9A 1202/4885MAPK1 1072/4885 |
| US-20180116221-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | PRXL2A, SHROOM3, NR2C2 | NPC1 4406/4885RAB9A 1131/4885MAPK1 1327/4885 |
| US-20020049194-A1 | Benzoheterocyclic derivatives | AVPR2, AVPR1A, AVPR1B | NPC1 2978/4885RAB9A 1825/4885MAPK1 1660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.