Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10789091 | 0.87 | NPC1 (0.68) | HTR1AADRA1DADRA1AADRA1BMAOB | |
| SCHEMBL17616586 | 0.85 | NPC1 (0.53) | HTR1AADRA1DADRA1AADRA1BMAOB | |
| SCHEMBL17616635 | 0.85 | MAOB (0.52) | HTR1AADRA1DADRA1AADRA1BMAOB | |
| SCHEMBL25394621 | 0.84 | MAOB (0.59) | HTR1AADRA1DADRA1AADRA1BMAOB | |
| SCHEMBL16273698 | 0.84 | MAOB (0.52) | HTR1AADRA1DADRA1AADRA1BMAOB | |
| SCHEMBL20425117 | 0.83 | CCR5 (0.58) | HTR1AADRA1DADRA1AADRA1BMAOB | |
| SCHEMBL17616612 | 0.81 | NPC1 (0.55) | HTR1AADRA1DADRA1AADRA1BMAOB | |
| SCHEMBL3359449 | 0.81 | HTR1A (0.52) | HTR1AADRA1DADRA1AADRA1BMAOB | |
| SCHEMBL5594953 | 0.81 | MAOB (0.55) | HTR1AADRA1DADRA1AADRA1BMAOB | |
| SCHEMBL16273706 | 0.80 | MAOB (0.51) | HTR1AADRA1DADRA1AADRA1BMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1099413-C | Certain fused pyrrolecarboxanilides, new class of gaba brain receptor ligands | NEUROGEN CORP (US) | 2003-01-22 | — | — | CN | disclosed |
| EP-0624155-B2 | CARBAMATES AND PLANT-PROTECTING AGENTS CONTAINING THEM | BASF AG (DE) | 2002-12-11 | — | — | EP | disclosed |
| US-6075148-A | CARBAMATE DERIVATIVES ARE USEFUL FOR CONTROLLING FUNGI, INSECTS, NEMATODES AND SPIDER MITES | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-13 | — | — | US | disclosed |
| US-5981532-A | FOR CONTROLLING FUNGI, INSECTS, NEMATODES AND SPIDER MITES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-09 | — | — | US | disclosed |
| US-5824705-A | FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-20 | — | — | US | disclosed |
| EP-0624155-B1 | CARBAMATES AND PLANT-PROTECTING AGENTS CONTAINING THEM | BASF AG (DE) | 1998-05-06 | — | — | EP | disclosed |
| CN-1143953-A | Certain fused pyrrolecarboxanilides, new class of gaba brain receptor ligands | NEUROGEN CORP (US) | 1997-02-26 | — | — | CN | disclosed |
| EP-0624155-A1 | CARBAMATES AND PLANT-PROTECTING AGENTS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1994-11-17 | — | — | EP | disclosed |
| WO-1993015046-A1 | CARBAMATES AND PLANT-PROTECTING AGENTS CONTAINING THEM | BASF AKTIENGESELLSCHAFT (DE) | 1993-08-05 | — | — | WO | disclosed |