Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10789091 | 0.87 | NPC1 (0.68) | HTR1AADRA1DADRA1AADRA1BNPC1 | |
| SCHEMBL10679738 | 0.82 | NPC1 (0.59) | HTR1AADRA1DADRA1AADRA1BNPC1 | |
| SCHEMBL7598113 | 0.81 | HTR1A (0.55) | HTR1AADRA1DADRA1AADRA1BNPC1 | |
| SCHEMBL5594953 | 0.81 | MAOB (0.55) | HTR1AADRA1DADRA1AADRA1BNPC1 | |
| SCHEMBL21545836 | 0.80 | KMT2A (0.59) | HTR1AADRA1DADRA1AADRA1BNPC1 | |
| SCHEMBL5483975 | 0.79 | HTR1A (0.56) | HTR1AADRA1DADRA1AADRA1BNPC1 | |
| SCHEMBL881475 | 0.77 | NPC1 (0.73) | NPC1RAB9ARECQLKMT2AALDH1A1 | |
| SCHEMBL3125878 | 0.77 | MAOB (0.68) | HTR1AADRA1DADRA1AADRA1BNPC1 | |
| SCHEMBL1520430 | 0.76 | ALDH1A1 (0.58) | NPC1RAB9ARECQLMAOBALDH1A1 | |
| SCHEMBL6221394 | 0.76 | NPC1 (0.66) | NPC1RAB9ARECQLKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123486-A1 | Photogenerated reagents | GAO XIAOLIAN (US) | 2013-05-16 | — | — | US | disclosed |
| US-8076501-B2 | Photogenerated reagents | LC SCIENCES LC | 2011-12-13 | — | — | US | disclosed |
| US-20100137600-A1 | Photogenerated reagents | LC SCIENCES LC | 2010-06-03 | — | — | US | disclosed |
| US-7544829-B2 | Photogenerated reagents | LC SCIENCES LC | 2009-06-09 | — | — | US | disclosed |
| US-20080009630-A1 | Photogenerated reagents | LC SCIENCES LC | 2008-01-10 | — | — | US | disclosed |
| US-7235670-B2 | Photogenerated reagents | Gao, Xiaolian | 2007-06-26 | — | — | US | disclosed |
| US-20060122408-A1 | Photogenerated reagents | LC SCIENCES LC | 2006-06-08 | — | — | US | disclosed |
| US-6965040-B1 | Photogenerated reagents | Gao, Xiaolian (US) | 2005-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123486-A1 | Photogenerated reagents | PPOX, PGR, GRHPR | HTR1A 2299/4885ADRA1D 4810/4885ADRA1A 4583/4885 |
| US-20080009630-A1 | Photogenerated reagents | PPOX, PGR, GRHPR | HTR1A 2299/4885ADRA1D 4810/4885ADRA1A 4583/4885 |
| US-20060122408-A1 | Photogenerated reagents | PPOX, PGR, GRHPR | HTR1A 2299/4885ADRA1D 4810/4885ADRA1A 4583/4885 |
| US-20100137600-A1 | Photogenerated reagents | PPOX, PGR, GRHPR | HTR1A 2299/4885ADRA1D 4810/4885ADRA1A 4583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.