Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 14/20 | 0.53 |
| ▸ | XIAP | P98170 | 4/20 | 0.47 |
| ▸ | CCKAR | P32238 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7849872 | 0.89 | PSEN1 (0.48) | CCKBRXIAP | |
| SCHEMBL6920745 | 0.82 | CCKBR (0.41) | CCKBRXIAP | |
| SCHEMBL4411787 | 0.81 | XIAP (0.48) | CCKBRXIAPCCKAR | |
| SCHEMBL4417220 | 0.74 | PSEN1 (0.59) | CCKBRXIAPCCKAR | |
| SCHEMBL7847907 | 0.74 | CCKBR (0.54) | CCKBRXIAPCCKAR | |
| SCHEMBL4424536 | 0.74 | XIAP (0.49) | CCKBRXIAPCCKAR | |
| SCHEMBL4417467 | 0.73 | PSEN1 (0.68) | — | |
| SCHEMBL6301491 | 0.71 | CCKBR (0.50) | CCKBRXIAPCCKAR | |
| SCHEMBL8020336 | 0.70 | ALDH1A1 (0.52) | CCKBRXIAP | |
| SCHEMBL17164501 | 0.70 | CTSK (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951466-A2 | CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | Elan Pharmaceuticals, Inc. (US) | 1999-10-27 | — | — | EP | disclosed |
| WO-1998028268-A2 | CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS AS β-AMYLOID PEPTIDE RELEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 1998-07-02 | — | — | WO | disclosed |