Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | F7 | P08709 | 2/20 | 0.36 |
| ▸ | F3 | P13726 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598497 | 1.00 | EPHX2 (0.39) | EPHX2ALDH1A1PPARGPPARAHCAR2 | |
| SCHEMBL7598506 | 1.00 | EPHX2 (0.39) | EPHX2ALDH1A1PPARGPPARAHCAR2 | |
| SCHEMBL7603138 | 0.87 | EPHX2 (0.38) | EPHX2ALDH1A1PPARGPPARAHCAR2 | |
| SCHEMBL7603151 | 0.87 | EPHX2 (0.38) | EPHX2ALDH1A1PPARGPPARAHCAR2 | |
| SCHEMBL7603148 | 0.87 | EPHX2 (0.38) | EPHX2ALDH1A1PPARGPPARAHCAR2 | |
| SCHEMBL7603840 | 0.84 | ALDH1A1 (0.47) | ALDH1A1PPARGPPARABLMHSD17B10 | |
| SCHEMBL7603837 | 0.84 | ALDH1A1 (0.47) | ALDH1A1PPARGPPARABLMHSD17B10 | |
| SCHEMBL27138529 | 0.84 | ALDH1A1 (0.47) | ALDH1A1PPARGPPARABLMHSD17B10 | |
| SCHEMBL7598503 | 0.81 | P2RY10 (0.32) | ALDH1A1LMNA | |
| Valiloxybate SCHEMBL3730350 | 0.80 | GABRP (0.42) | ALDH1A1PPARGPPARABLMPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002503673-A | — | — | 2002-02-05 | — | — | JP | claimed |
| EP-1054891-A1 | PRODRUGS | MEDIVIR AB (SE) | 2000-11-29 | — | — | EP | claimed |
| WO-1999041275-A1 | PRODRUGS | MEDIVIR AB (SE) | 1999-08-19 | — | — | WO | claimed |