Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY10 | O00398 | 6/20 | 0.32 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.30 |
| ▸ | DGKA | P23743 | 2/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603141 | 0.88 | IARS1 (0.32) | P2RY10GPR34GPR174 | |
| SCHEMBL7598508 | 0.81 | EPHX2 (0.39) | ALDH1A1LMNA | |
| SCHEMBL7598497 | 0.81 | EPHX2 (0.39) | ALDH1A1LMNA | |
| SCHEMBL7598506 | 0.81 | EPHX2 (0.39) | ALDH1A1LMNA | |
| SCHEMBL27165965 | 0.77 | ALDH1A1 (0.35) | P2RY10GPR34PRSS1PRSS2PRSS3 | |
| SCHEMBL14095430 | 0.75 | SLC7A5 (0.42) | ALDH1A1NAAA | |
| SCHEMBL26231092 | 0.75 | SLC7A5 (0.42) | ALDH1A1NAAA | |
| SCHEMBL26231086 | 0.75 | SLC7A5 (0.42) | ALDH1A1NAAA | |
| SCHEMBL6368605 | 0.73 | SLC7A5 (0.44) | ALDH1A1NAAA | |
| SCHEMBL8635690 | 0.72 | ALDH1A1 (0.41) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002503673-A | — | — | 2002-02-05 | — | — | JP | claimed |
| EP-1054891-A1 | PRODRUGS | MEDIVIR AB (SE) | 2000-11-29 | — | — | EP | claimed |
| WO-1999041275-A1 | PRODRUGS | MEDIVIR AB (SE) | 1999-08-19 | — | — | WO | claimed |