Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10609772 | 0.89 | CA4 (0.40) | — | |
| Hydrochloric Acid SCHEMBL723144 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL872861 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL28460034 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL446648 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL27977492 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL18555695 | 0.82 | — | — | |
| Water SCHEMBL15966592 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL11396535 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL6308229 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263960-A2 | ANTI-TISSUE FACTOR ANTIBODIES WITH ENHANCED ANTICOAGULANT POTENCY | Genentech, Inc. (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001070984-A2 | ANTI-TISSUE FACTOR ANTIBODIES WITH ENHANCED ANTICOAGULANT POTENCY | GENENTECH, INC. (US) | 2001-09-27 | — | — | WO | disclosed |