SCHEMBL7598774

SCHEMBL7598774

CCc1ccc(-c2cccc3c2C=C(C)C3[Zr](Cl)Cl)cc1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 1/20 0.34
EDNRA P25101 1/20 0.34
S1PR1 P21453 1/20 0.30
S1PR5 Q9H228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27565547 0.89 CD274 (0.36)
SCHEMBL27670433 0.88 EDNRB (0.35) EDNRBEDNRA
SCHEMBL28822509 0.87 HSD11B1 (0.36)
SCHEMBL27463310 0.87 CALM1 (0.31)
SCHEMBL27513128 0.86 EDNRB (0.34) EDNRBEDNRAS1PR1S1PR5
SCHEMBL6889133 0.86 EDNRB (0.32) EDNRBEDNRA
SCHEMBL27570795 0.85 HSD11B1 (0.40)
SCHEMBL27463750 0.85 PTGS2 (0.33) EDNRBEDNRA
SCHEMBL3163967 0.84 BRD4 (0.33)
SCHEMBL6055702 0.84 EDNRB (0.33) EDNRBEDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100575324-C Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins BASELL POLYPROPYLEN GMBH 2009-12-30 CN disclosed
CN-1249096-C Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins BASELL POLYPROPYLEN GMBH (DE) 2006-04-05 CN disclosed
CN-1590355-A Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins BASELL POLYPROPYLEN GMBH (DE) 2005-03-09 CN disclosed
CN-1590422-A Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins BASELL POLYPROPYLEN GMBH (DE) 2005-03-09 CN disclosed
CN-1138680-C Container for heating and sterilizing ������ѧ��ʽ���� 2004-02-18 CN disclosed
CN-1433435-A Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins BASELL POLYPROPYLEN GMBH (DE) 2003-07-30 CN disclosed
EP-1263847-A1 PROCESS FOR THE PREPARATION OF ADDITIVE COATED MOLDING POWDER Borealis Technology Oy (FI) 2002-12-11 EP disclosed
WO-2001062832-A1 PROCESS FOR THE PREPARATION OF ADDITIVE COATED MOLDING POWDER BOREALIS TECHNOLOGY OY (FI) 2001-08-30 WO disclosed
EP-1123319-A2 SUPPORTED POLYMERIZATION CATALYSTS Borealis Technology (FI) 2001-08-16 EP disclosed
WO-2000022011-A2 SUPPORTED POLYMERIZATION CATALYSTS BOREALIS TECHNOLOGY OY (FI) 2000-04-20 WO disclosed